Words similar to nestin
Example sentences for: nestin
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For quantification of cells expressing Nestin, Ki67, β-tubulin III, activated caspase-3, insulin, or C-peptide, NS-derived cell clusters were fixed, and sectioned to generate 7-μm-thick tissue sections.
(NM_002181), Isl1 (NM_002202), MAP2 (U01828), myelin basic protein (M13577), myosin light chain-2 (X57542), Nestin (NM_006617), ngn3 (AF234829), Nkx6.
Recent experiments by Fults and colleagues support the idea that stabilized β-catenin expression in the postnatal CNS is not sufficient to initiate tumor formation [ 36 ] . Using the RCAS-TVA system they showed that overexpression of c-myc, but not of activated β-catenin, promoted the proliferation of neural progenitor cells in vivo and in vitro . In their in vivo experiments expression was initiated in nestin positive cells postnatally via injection of β-catenin stabilized by a point mutation in codon 37.
Isolated human neural progenitors spontaneously aggregate in these conditions to produce a cell cluster called a NS, and 85%–90% of NS cells produce the intermediary filament Nestin (Figures 1 and 2), a putative marker of neural stem and progenitor cells [19].
In stage 3 cultures, Nestin and Ki67 expression was nearly extinguished (see Figure 2), while expression of En1, ngn3, and Hb9 increased (see Figure 1B and 1C).