Example sentences for: nephrotoxicity

How can you use “nephrotoxicity” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The dosage of colistin used in our study was more than double that usually recommended [ 9 10 12 ] , although much higher doses - with a parallel increase in nephrotoxicity - have been reported in the past [ 23 ] . We opted for the higher dose because of the severity of the infections being treated.

  • Among the adverse effects of vancomycin (apart from nephrotoxicity and ototoxicity), anaphylactoid reactions may occur, which manifest clinically as cutaneous rash, pruritus ('red man' syndrome), hypotension and broncospasm [ 4, 8, 9].

  • On the other hand, experience with the drug in patients with cystic fibrosis, has shown only minimal nephrotoxicity [ 19 20 21 30 ] . Garnacho-Montero and coworkers [ 12 ] , in patients with VAP, observed that there was no significant difference in development of renal failure between colistin and imipenem.

  • Providers may also be concerned about the nephrotoxicity of certain antiretroviral agents, notably indinavir-associated crystal induced renal failure, [ 22 ] and other antiretroviral agents that require dose adjustment in renal failure.

  • Levin and coworkers [ 9 ] also reported a high incidence of nephrotoxicity (37%), especially in patients who already had compromised renal function [ 9 ] . Because most of the patients in both studies were seriously ill, it is highly probable that at least part of the reported toxicity was the result not of the drug but of the disease.


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