Words similar to nephrosclerosis

Example sentences for: nephrosclerosis

How can you use “nephrosclerosis” in a sentence? Here are some example sentences to help you improve your vocabulary:

While other animal models of hypertension can be employed to study the pathogenesis of hypertension, because of the rapid and reproducible development of renal failure, S rats provide a unique means to investigate the pathogenesis of hypertensive nephrosclerosis.
The role of the Fas/FasL pathway in human hypertensive nephrosclerosis remains to be determined.
Recent studies have shown that apoptosis was accentuated in kidneys of S rats during development of nephrosclerosis [ 7 ] . These studies demonstrated increased numbers of TUNEL-positive cells, increased cytoplasmic nucleosome content and caspase-3 activation in kidneys of hypertensive S rats, compared to normotensive Sprague-Dawley control rats on the same high-salt diet.
In kidneys of S rats, associated with apoptosis was a temporal increase in expression of Fas, which was demonstrated using Western analysis of lysates of kidney cortex [ 7 ] . The purpose of the present study was to demonstrate the site of expression and potential functional significance of Fas and FasL in the kidneys of S rats during development of hypertensive nephrosclerosis.
A previous study suggested that the apoptotic process occurred early in the development of hypertension in this model [ 26 ] , so the data suggested that an apoptotic mechanism in addition to activation of the Fas/FasL pathway is also involved in development of hypertensive nephrosclerosis in S rats.