Words similar to neoplastic
Example sentences for: neoplastic
How can you use “neoplastic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Converging points of evidence implicate infection by high-risk human papilloma virus (HPV) types as a critical etiologic factor in cervical tumorigenesis [ 1 ] . Epidemiological and experimental data, however, show that only a small fraction of HPV-infected cervical intraepithelial neoplastic (CIN) lesions progress to invasive cervical carcinoma (CC) [ 2 ] . These findings suggest somatic genetic mutations play a critical role in the initiation and progression of CC.
A thorough understanding of the neoplastic process could facilitate earlier detection of the disease, lead to more specific therapies for PCA, and ultimately improve survival.
1. Not all precancers are neoplastic.
It is well established that mutations affecting the guanine nucleotide state of Ras are associated with neoplastic transformation of mammalian cells [ 35 72 73 ] . However, the potential role of Rab mutations in disease is just beginning to be explored.
Converging evidence from epidemiological and molecular studies suggests that infection of genital human papillomavirus (HPV) is causally linked to the development of CC [ 4 ] . Since only a small fraction of HPV-infected cervical intra-epithelial neoplastic (CIN) lesions progress to invasive cancer, these studies further suggest that in addition to HPV, other host genetic factors play a role in cervical carcinogenesis [ 5 ] . A number of molecular studies have identified genetic alterations in these two histologic types of CC and at various stages of precursor lesions [ 6 7 8 ] . Despite this molecular characterization, the genetic basis of CC initiation and progression is still very poorly understood.
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