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Example sentences for: neonates
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[ 12 ] tested preferred tail direction in neonates exposed in utero to EtOH.
Similar results were reported by other authors [ 15 16 17 ] . These results demonstrate that the cultured rib chondrocytes behaved in a similar manner as chondrocytes in vivo . Taken together, primary rib chondrocytes from mouse neonates grown in micromass culture display cellular differentiation, proliferation, maturation and hypertrophy, recapitulating the chondrocyte maturation program in vivo . These results establish the utility of this in vitro system to investigate the role of Hox genes and other transcription factors in endochondral ossification.
[ 21 ] ), a growing body of research also suggests that there might be increased vulnerability during the neonatal period [ 15 16 17 ] . The fact that the blood-brain barrier is incomplete [ 34 ] , provides a putative explanation as to why neonates and fetal mice in utero appear to be more sensitive to neurotoxins like domoic acid than adult animals [ 35 36 37 ] . Although microglia contribute to circa 10% of the total glial cell population in the central nervous system (For review see Ref.
Targeted null Brn3c mutants have no mature hair cells [ 1 2 ] . Close examination has revealed that some 'immature' hair cells form in Brn3c null mutants and express cellular markers such as Myosin VI and VIIa, calretinin and parvalbumin [ 3 ] . Furthermore, these immature hair cells of Brn3c null mutants undergo apoptosis in neonates [ 3 ] . Consistent with an apparent absence of mature hair cells, initial work suggested that all vestibular and most spiral ganglion cells are lost by postnatal day 14 (P14; [ 1 ] ). However, more detailed quantification by others [ 3 ] reported that at P4 about 77% of vestibular neurons and only 29% of spiral neurons are lost.
Interestingly, the gender differences in heart rate we observed in adult mice were absent in 6-day old and 12-day old neonates.
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