Example sentences for: negatively

How can you use “negatively” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Compound 12b contains additional negatively charged substituents that may facilitate Fhit inhibition [ 15 ] while rendering the compound antagonistic to Fhit function in the cell.

  • Gaps represented by Ns were not given a consensus quality score and did not contribute negatively to the estimated error rate.

  • In the presence of the EGFR, ligand activation of LPA and ET-1 receptors did not increase EGFR phosphorylation even though both the LPA and ET-1 receptors stimulated ERK activity by 10-fold over basal [ 27 ] . Specifically, key protein intermediates may be physically associated with endogenous RTKs in HEK-293 cells, and therefore, down-regulation of the EGFR may negatively affect ERK phosphorylation by opioids.

  • Attachment involves noncovalent interactions such as electrostatic interactions, where the negatively charged phosphate backbone of the oligonucleotide is attracted to the positively charged surface of the glass slide (for example, a surface containing protonated alkyl amines).

  • An R:S that is found to be higher than expected indicates that the replacement mutation tested is positively selected, while a lower-than-expected observed R:S indicates that the tested replacement mutation is negatively selected.


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