Words similar to negatively
Example sentences for: negatively
How can you use “negatively” in a sentence? Here are some example sentences to help you improve your vocabulary:
Metabotropic glutamate receptors (mGluRs) are a family of class 3 G protein-coupled receptors with important functions in the regulation of synaptic transmission, plasticity, neuronal excitability, and the regulation sensory transduction [ 1 2 3 4 5 ] . The eight mGluRs (mGluR1-8) and their splice variants have been divided into three groups (I-III) based on sequence homology, pharmacology and G protein coupling profiles [ 3 6 7 ] . Group II (mGluR2 and 3) and III (mGluR4, and 6 through 8) couple negatively to adenylate cyclase through activation of the G i/o family of G proteins [ 8 ] . Group I mGluRs (mGluR1 and 5) couple to multiple G proteins in native and heterologous systems, and have been observed to couple to G q/11 , G i/o and/or G s [ 9 10 11 12 13 14 15 ] . mGluRs appear to be important mediators of synaptic transmission in the brain.
Control of secretion is complex and involves several proteins that positively and negatively regulate the activity of the secretion apparatus in response to environmental conditions [ 3 ] . LcrG has been implicated in blocking the secretion apparatus either directly or indirectly [ 4 ] , as strains lacking lcrG constitutively secrete Yops [ 5 ] , regardless of inducing conditions.
The determination of HFC is highly influenced by absolute expression, and trends can be readily observed in our data set where HFC is negatively correlated with absolute expression (Figure 1a).
Replacement of this aspartic acid residue even by the negatively charged glutamic acid (a very close analog of aspartic acid) did not significantly suffice to restore a full inhibitory activity of PAI-1 (Fig.
Our work [ 6 11 ] and most other work indicates that the cell density dependent mechanisms that negatively regulate cell proliferation are dominant to Tag.
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