Words similar to naltrindole
Example sentences for: naltrindole
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In C6 glioma cells that express the mouse δ-OR, DSLET produced a concentration-dependent increase in the appearance of phospho-ERK 1 and 2. DSLET-mediated ERK activation in C6-δ-OR cells was completely inhibited by either pre-treatment with PTX or naltrindole (data not shown).
Pretreating the cells with PTX (100 ng/ml), or the specific δ-OR antagonist, naltrindole (10 μM), completely blocked the DSEET-induced increase in ERK phosphorylation (Figure 1b).
The opioid agonist, [D-Ser-Leu-enkephalin-Thr (DSLET), was received from the National Institute of Drug Abuse (NIDA, Baltimore, MD) and the antagonist, naltrindole, was purchased from Research Biochemicals, Inc., (Natick, MA).
1 μM DSLET-induced tyrosine phosphorylation of the δ-OR was inhibited by naltrindole, PP1, but not by AG1478 (Figure 5).
Third, in rat spinal cord ( 12), we found that preincubation of fixed tissue with specific δ-opioid ligands (DADLE, Met-enkephalin, dermenkephalin and naltrindole at 10 -9M) totally prevented the antibody labeling, showing a good competition between ligands and the anti-Id mAb.