Example sentences for: nalbuphine

How can you use “nalbuphine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Two ligands, nalbuphine and naltrexone were categorized as antagonists.

  • The rank order of efficacy of the ligands tested were fentanyl = hydromorphone = β-endorphin > etorphine = lofentanil = butorphanol = morphine= nalbuphine = nalorphine > cyclazocine = dezocine = metazocine ≥ xorphanol.

  • The other ligands, met-enkephalin, WIN 44,441, hydromorphone and Butorphanol, exhibited potencies of 10-100 nM; metazocine and SKF 10047, 100-200 nM, and nalbuphine, dezocine and morphine, 400-1000 nM.

  • This can explain the usefulness of drugs such as nalbuphine in reducing the side effects associated with the more potent opioid analgesics while not totally reversing the analgesic action of those ligands.

  • Therefore, if combined with a drug such as fentanyl, or in the presence of an internal pool of β-endorphin, nalbuphine can act as an antagonist in inhibiting adenylyl cyclase by μ opioid receptors.


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