Words similar to n-c

Example sentences for: n-c

How can you use “n-c” in a sentence? Here are some example sentences to help you improve your vocabulary:

The finding that estrogens suppress N-CoR binding to ERα [ 39 ] , but promote N-CoR binding to ERβ represents the first demonstration of a corepressor that shows completely distinct modes of hormone-dependent interaction with the ER isoforms.
NR interactions with N-CoR are usually mediated by a hydrophobic cleft that spans residues from H3 and H5 and includes residues that lie under H12 in the liganded configuration [ 4 17 ] . These interactions are either independent of, or inhibited by, NR H12 [ 17 39 42 ] . By contrast, NR interactions with coactivators are mediated by residues from the upper part of H3-H5 and also require H12 itself [ 18 ] . Fig.
However, ERβ did bind to a fragment that spanned the extreme C-terminus (2322-2453) and did so in a manner that was promoted by E2 and suppressed by ICI, much like the interactions of ERβ with the entire N-CoR nuclear receptor interacting region.
Binding of ERβ to N-CoR (2322-2453) is probably very efficient for two reasons.
A mutation (PL T IRML>PL L IRML) that restores the LXXLL consensus increases ERβ binding to N-CoR and permits ERα to bind to N-CoR in the presence of estrogens in mammalian two-hybrid assays.