Example sentences for: n-c
How can you use “n-c” in a sentence? Here are some example sentences to help you improve your vocabulary:
Mutation of N-CoR to obtain a β-box sequence that more closely resembled a conventional LXXLL motif (T2402L) led to enhanced hormone-dependent interactions with ERβ and permitted novel hormone-dependent interactions with ERα (Fig.
Moreover, results from the two-hybrid assay indicate that the ERβ LBD is sufficient to obtain estrogen-dependent interactions with N-CoR.
To create the expression vectors for the smaller fragments, truncated N-CoR polypeptides that were obtained in E. Coli extracts were subjected to protein sequence analysis and cDNA fragments that coded for the major truncated products were prepared.
Together, our results indicate that ERβ has the potential to utilize its AF-2 surface to bind NR boxes within coactivators or an NR box-like sequence in the C-terminus of N-CoR.
To map the region of N-CoR that interacted with ERβ, we examined ERβ binding to a series of rationally designed smaller fragments of the N-CoR C-terminus (Fig.