Words similar to n-c

Example sentences for: n-c

How can you use “n-c” in a sentence? Here are some example sentences to help you improve your vocabulary:

Since ERβ bound N-CoR and SMRT in the presence of estrogens, we investigated the possible involvement of corepressors in the actions of agonist-bound ERβ in vivo . To perform this experiment, we examined the effect of the HDAC inhibitor trichostatin A (TSA) on ERβ activity in transiently transfected HeLa cells.
6Ashows, a synthetic β-box peptide competed for binding to N-CoR, albeit somewhat less efficiently than native GRIP1 NR box 2. Similar results were obtained in competition experiments that used GST-GRIP1 instead of GST-N-CoR (data not shown).
A mutation (PL T IRML>PL L IRML) that restores the LXXLL consensus increases ERβ binding to N-CoR and permits ERα to bind to N-CoR in the presence of estrogens in mammalian two-hybrid assays.
Finally, mutations within the β-box (especially M2405A, L2406A) disrupted ERβ interactions with N-CoR in mammalian two-hybrid assays, but did not affect TRβ interactions (Fig.
Thus, the β-box is sufficient to bind ERβ and is essential for agonist-dependent ERβ interactions with the N-CoR C-terminus.