Example sentences for: n-c
How can you use “n-c” in a sentence? Here are some example sentences to help you improve your vocabulary:
Agonist Dependent ERβ Interactions with N-CoR and SMRT
NRs generally interact with the corepressors N-CoR and SMRT either in the absence of ligand, or in the presence of receptor antagonists, and agonists promote corepressor release [ 4 ] . In this study, we demonstrated that ERβ binds to N-CoR in the presence of ER agonists such as estradiol and DES and the phytoestrogens genistein and coumestrol, but not in the presence of SERMs.
Directed studies of NR interactions with N-CoR and provided intellectual input into study design.
Second, as developed above, preparations of N-CoR (1944-2453) generally contain truncated products, so sequences corresponding to the extreme N-CoR C-terminus (which binds ERβ) is markedly under-represented.
However, ERβ did bind to a fragment that spanned the extreme C-terminus (2322-2453) and did so in a manner that was promoted by E2 and suppressed by ICI, much like the interactions of ERβ with the entire N-CoR nuclear receptor interacting region.