Example sentences for: n-c
How can you use “n-c” in a sentence? Here are some example sentences to help you improve your vocabulary:
The unliganded LBD recognizes hydrophobic motifs, termed interaction domains (IDs), which are reiterated three times in N-CoR and twice in SMRT and conform to the consensus L/IXXIIXXXL [ 4 ] (see also [ 16 ] ). By contrast, the liganded LBD binds shorter hydrophobic motifs termed NR boxes that are reiterated several times within each coactivator and conform to the consensus LXXLL.
The N-CoR C-terminus contains the sequence PLTIRMLS (β-box, amino acids 2399-2406; Fig.
Since ERβ bound N-CoR and SMRT in the presence of estrogens, we investigated the possible involvement of corepressors in the actions of agonist-bound ERβ in vivo . To perform this experiment, we examined the effect of the HDAC inhibitor trichostatin A (TSA) on ERβ activity in transiently transfected HeLa cells.
We investigated the significance of the β-box in ERβ interactions with N-CoR.
Control binding experiments performed in parallel confirmed that ERα bound to N-CoR in the presence of SERMs, and not estradiol (Fig.
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