Example sentences for: n-butyrate

How can you use “n-butyrate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Two of three cell lines with RASSF1A methylation and complete lack of expression reactivated upon treatment with 5-Aza-2' deoxycytidine alone or in combination with n-butyrate.

  • Cell lines were treated with demethylating agent 5-Aza-2' deoxycytidine (Sigma) for five days at a concentration of 2 to 5 μM, HDAC-inhibiting agent n-butyrate at a final concentration of 5 μM for the last 24 hours or a combination of both.

  • The SW756 cell line with methylation and one of the two unmethylated cell lines showed reactivated expression upon treatment with 5-Aza-2' deoxycytidine or in combination with n-butyrate, but not with n-butyrate alone.

  • Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment with the hypo-methylating agent 5-aza-2'-deoxycytidine and HDAC-inhibiting agent n-butyrate in a dose and duration-dependent manner.

  • Treatment of 5-Aza-2' deoxycytidine or n-butyrate alone or the combination of both activated gene expression in all the cell lines, whether or not promoter had detectable methylation (Fig.


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