Words similar to myristate
Example sentences for: myristate
How can you use “myristate” in a sentence? Here are some example sentences to help you improve your vocabulary:
The following results support this hypothesis: 1) sα i2 and α i2 are equally labeled by a pulse of 3H-myristate, although much less sα i2 protein is detected; 2) sα i2 displays a propensity to localize to potential aggresome-like structures, and this localization is greatly enhanced by proteasome inhibitor treatment; 3) the α i2 A327S mutant, previously shown to be unstable and defective in guanine-nucleotide binding, shows a similar pattern of subcellular localization ( i.e., intracellular membranes rather than PM); 4) βγ over-expression increases expression of sα i2 and promotes PM localization of sα i2 and α i2 A327S, but βγ co-expression does not prevent sα i2 localization to potential aggresome-like structures when cells are treated with proteasome inhibitors; and 5) pulse-chase analysis indicates that sα i2 is rapidly degraded.
In contrast, both α i2 and sα i2 incorporated similar levels or myristate (Figure 6A, lanes 5 and 6).
Phorbol 12-myristate 13-acetate (PMA) is a specific activator of group A and group B protein kinase C. We wanted to determine, therefore, if protein kinase C activation by PMA would enhance the toxicity of CEES.
Accordingly, the myristoylation results (Figure 6Aand 6B, lanes 5 and 6) strongly suggested that α i2 and sα i2 are translated equally well, as evidenced by similar levels of radiolabeled myristate incorporation during the labeling period, but sα i2 is more rapidly degraded, as seen by reduced steady-state levels of immunoprecipitated protein.
5 μM; Sigma), phytohemagglutinin (2 μg/ml; Wellcome Diagnostics, Greenville, NC, USA), and phorbol myristate acetate (20 ng/ml; Sigma) in the presence of monensin (2 μM; Sigma) for 6 h and were fixed in paraformaldehyde for subsequent intracellular cytokine analysis.
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