Example sentences for: myristate

How can you use “myristate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Phorbol 12-myristate 13-acetate (PMA) and ionomycin were purchased from Sigma (St.

  • While most cytokine research has focused on cells of the immune system, other cell types produce cytokines including the epithelial cells of the lung [ 28 29 ] , retina [ 30 ] , and intestines [ 31 32 ] . Among the few studies involving the biliary system, it was demonstrated that cultured human intrahepatic duct epithelial cells produce functional IL-8 and MCP-1 (CCL2) [ 14 33 ] . Isolated human intrahepatic epithelial ducts expressed immunoreactive IL-6 when treated with IL-1β or phorbal myristate acetate [ 34 ] . Intracellular TNF-α mRNA and protein was detected in intrahepatic biliary duct cells in tissue sections [ 35 ] , but not in cultured intrahepatic epithelial cells; therefore, there was no clear demonstration that biliary epithelium secretes TNF-α.

  • Phorbol 12-myristate 13-acetate (PMA) is a specific activator of group A and group B protein kinase C. We wanted to determine, therefore, if protein kinase C activation by PMA would enhance the toxicity of CEES.

  • Myristoylation occurs co-translationally at the extreme N-terminal glycine, while palmitoylation occurs post-translationally at a cysteine immediately after the myristoylated glycine [ 15 ] . The subcellular site where palmitoylation occurs has not been well defined, although in one model palmitoylation occurs at the PM [ 16 ] . Cells expressing α i2 or sα i2 were metabolically labeled with 3H-palmitate or 3H-myristate.

  • EC, endothelial cell; MMP, matrix metalloproteinases; 3D, three-dimensional; KDR, kinase domain receptor; SSHDD, suppression subtractive hybridization followed by differential display; VE-cadherin, vascular endothelial-cadherin; PMA, phorbol 12-myristate 13-acetate; VEGF, vascular endothelial growth factor; bFGF, basic fibroblast growth factor.


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