Words similar to myristate
Example sentences for: myristate
How can you use “myristate” in a sentence? Here are some example sentences to help you improve your vocabulary:
Virus infectivity can be enhanced by treatment of cells with MAPK stimulators, such as serum and phorbol myristate acetate, as well as by coexpression of constitutively activated Ras, Raf, or MEK in the absence of extracellular stimulation [ 61 ] . Also, following infection, efficient disengagement of the reverse transcription complex from the cell membrane and subsequent nuclear translocation, requires phosphorylation of the reverse transcription complex components by ERK/MAPK; demonstrating a critical regulation of an early step in HIV-1 infection by the host cell MAPK signal transduction pathway [ 62 ] . Therefore, Tat down-regulation of the MAPK pathway in latent cells implies that much of the host signal transductions connected to activation are down-regulated, and at the same time, these cells may be refractory to subsequent infection by other viruses.
Accordingly, the myristoylation results (Figure 6Aand 6B, lanes 5 and 6) strongly suggested that α i2 and sα i2 are translated equally well, as evidenced by similar levels of radiolabeled myristate incorporation during the labeling period, but sα i2 is more rapidly degraded, as seen by reduced steady-state levels of immunoprecipitated protein.
Nigericin, Monensin, Phorbol 12-myristate 13-acetate (PMA), horseradish peroxidase (HRP, type IV) and hydrogen peroxide (H 2 O 2 ) were purchased from Sigma (St.
Louis, MO) and phorbol 12-myristate 13-acetate was from Calbiochem (La Jolla, CA).
The tumor promoter phorbol myristate acetate (PMA) has been shown to activate the NADPH (nicotinamide adenine dinucleotide phosphate) oxidase and initiate the oxidative burst response in various phagocytes, including neutrophils and the macrophage-like cell line J774A.
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