Example sentences for: murine

How can you use “murine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Proteoglycan-induced arthritis (PGIA) is a novel autoimmune murine model that is induced by systemic immunization of BALB/c mice with cartilage proteoglycans [ 12 13 ] . The development of PGIA is based on the cross-reactive immune response between immunizing human and mouse (self) cartilage proteoglycans in genetically susceptible BALB/c mice [ 12 13 ] . Several lines of evidence indicate T-cell involvement in the pathogenesis of PGIA.

  • The deduced protein sequence is identical to a reported murine sequence (AF302844), but has an Ile-355 to Val-355 transition compared to another clone (AF302843).

  • Mills and Gordon recently studied the relative contribution of experimental variability of probe production on the reproducibility of microarray results using mixed murine tissue RNA on Affymetrix Mu11K GeneChips [ 20 ] . In their study, the same RNA preparation was used as a template for distinct cDNA/cRNA amplifications and hybridizations.

  • However, the potential to induce the dioxygenase in murine systems by IFN-γ exposure has been demonstrated when nitric oxide production is blocked [ 41].

  • Interestingly, local expression of murine TNF-α mRNA was not affected by treatment with anti-TNF-α antibodies, suggesting that hTNF-α plays a crucial role in the pathogenesis of arthritis in this model.


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