Words similar to multimerized

Example sentences for: multimerized

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The binding site for the DBD is multimerized into a concatameric array which is then inserted into the genome of animal or yeast cells.
Two families of small peptides binding to the human thrombopoietin receptor (TPOR) were isolated that competed with the natural ligand TPO [ 34 ] . The peptide with the highest affinity was subsequently dimerized and shown to function as a potent TPO agonist in vivo . Recently, a small, non-peptide organic molecule binding to one chain of the EPO receptor was multimerized and shown to mimic the biological activities of the EPO [ 35 ] .
Short defined cDNA sequences are initially prepared from mRNA which are then dimerized, multimerized, cloned, and sequenced [ 20 ] . SAGE accelerated the process of gene expression analysis more than an order of magnitude compared to the conventional EST analysis and still is compatible with most of the improvements of DNA sequencing mentioned above.
We then introduced into each line a plasmid containing a luciferase reporter downstream of multimerized Gli binding sites and a minimal promoter [ 20 ] . An isolated stable clone of the 10T1/2 cell transfectants (referred to as clone S12) gave a 10-20-fold up-regulation of luciferase activity (Figure 1a) when stimulated with Hh protein [ 21 ] for 24 hours.