Words similar to multidomain
- multicultural
- multiculturalism
- multiculturalists
- multiculturally
- multidialectal
- multidimensional
- multidimensionalsearch
- multidirectionally
- multidisciplinary
- multidomain
- multidomestic
- multidrug
- multidrug-resistance
- multidrug-resistant
- multiecho
- multiexponential
- multifaceted
- multifactorial
- multilateral
- multilingual
Example sentences for: multidomain
How can you use “multidomain” in a sentence? Here are some example sentences to help you improve your vocabulary:
The majority of the domains with which the KilA-N and Bro-N domains combine in multidomain proteins are restricted to proteins encoded by temperate bacteriophages and large eukaryotic DNA viruses (the exceptions are a few domains that are common in cellular proteomes, such as HTH, CCCH and RING finger).
Gene fusion leading to the formation of multidomain proteins is one of the major routes of protein evolution.
In order to identify the entire repertoire of domains involved in these domain-shuffling events, we systematically explored all domains that combined with the KilA-N and Bro-N domains and compiled a list of domains with which the latter combined in other multidomain proteins (Table 2, Figure 2a).
Typically, these domains were identified in multidomain proteins that additionally contained several previously undetected, evolutionarily mobile domains occurring in different contexts.
TSP-1 is a homotrimeric multidomain glycoprotein synthesized and secreted by numerous cell types, including platelets, vascular smooth muscle cells and keratinocytes [ 4 ] . Due to its interaction with a wide variety of proteins, TSP-1 has been implicated in a number of biological processes including coagulation, cell adhesion, the modulation of cell-cell and cell-matrix interactions, control of tumor growth and metastasis, and angiogenesis [ 10 ] . Inhibition of tumor cell proliferation has been achieved in vivo by systemic treatment with TSP-1 peptide mimetics [ 11 ] , but a correlation between primary tumor TSP-1 expression and poor prognosis has not been clearly established [ 12 ] . While there are reports that these molecules can originate from tumor cells [ 13 ] , the majority of reports have suggested that the major source of both TSP-1 and OPN is tumor-associated stroma [ 14 ] or infiltrating macrophages and lymphocytes [ 15 ] .
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