Words similar to mtx-induced
Example sentences for: mtx-induced
How can you use “mtx-induced” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although elevating [Ca 2+] i with ionomycin had no effect on vital dye uptake, preliminary experiments in which fibroblasts were loaded intracellularly with the Ca 2+chelator BAPTA, showed that MTX-induced responses were significantly delayed, suggesting that a rise in [Ca 2+] i is necessary, but not sufficient for MTX-induced COP formation.
Stimulation of P2X purinergic receptors by ATP causes similar changes in cytosolic Ca 2+and vital dye uptake [ 10, 11, 12, 13, 14, 15, 16, 17] suggesting that MTX activates a cell death cascade that is physiologically relevant, although the exact role of either the P2X- or MTX-induced cascade in normal cellular biology remains unknown.
First, U73122 and U73343, compounds that are commonly used to examine PLC-dependent mechanisms, potently inhibit MTX-induced change in [Ca 2+] i , vital dye uptake, and oncotic cell death in BAECs.
An example of MTX-induced membrane blebs is shown in the micrograph in Fig 5which was obtained with Hoffman optics and simultaneous bright-field and fluorescence illumination.
As seen in Fig 5, and in each of these videos, MTX-induced blebbing results in an enormous increase in membrane surface area which may represent stretching of the membrane or an evagination of existing caveolar structures associated with the plasmalemma of endothelial cells.
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