Words similar to mtx-induced

Example sentences for: mtx-induced

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The initial MTX-induced increase in [Ca 2+] i reflects the activation of a Ca 2+-permeable non-selective cation channel (CaNSC) [ 1 4 5 6 7 8 ] . This channel, which has a reported conductance in the range of 12-40 pS depending on ionic conditions [ 5 9 10 11 ] , causes rapid membrane depolarization, which in excitable cells, leads to activation of voltage-sensitive channels.
MTX-induced enhancement of 5-phosphoribosyl-1-pyrophosphate (PRPP) pools with subsequent increased synthesis of 5-FU nucleotides and incorporation of 5-fluoriuridine - 5'-triphosphate (FUTP) into RNA has been proposed as the basis for this biochemical modulation.
MTX-induced EB uptake and membrane blebbing in single BAECs.
Another class of compounds known as imidazoles, of which SKF 96365 is the best studied, have also been shown to block MTX-induced responses in many cell types [ 5 7 12 28 ] . The imidazoles, which are antifungal agents that inhibit cytochrome P 450 , are relatively non-selective and are known to block voltage-gated Ca 2+channels and receptor-activated Ca 2+influx through so-called store-operated channels (SOCs) [ 29 ] , but their mechanism of action in this regard remains unknown.
U73343 rescues cells from MTX-induced oncotic cell death.