Words similar to mtx
Example sentences for: mtx
How can you use “mtx” in a sentence? Here are some example sentences to help you improve your vocabulary:
Rheumatoid arthritis (RA) is a significant, chronic disease that afflicts 1% of the general population in most countries [ 1 ] . Joint damage typically occurs before patients are diagnosed, and most of the joint destruction occurs within the first 2 years of diagnosis [ 2 ] . Therapeutic drugs such as sulfasalazine and methotrexate (MTX) only slow the progression of the disease, suggesting that these drugs fail to adequately quell the underlying pathophysiology of RA [ 3 ] .
When U73343 is added at longer times, a large proportion of the cells challenged by MTX have apparently passed a point-of-no-return and are destined to die by oncosis.
A significant increase in caspase-3 activity (p < 0.035; n = 3) was observed in cells challenged with MTX and subsequently rescued by U73343, consistent with increased apoptotic cell death.
In conclusion, MTX treatment of BAECs causes a specific sequence of events (i.e.
At 1 nM MTX, the number of BAECs that undergo zeiosis in the presence of U73343 is increased (see Additional File 3).
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