Example sentences for: msp

How can you use “msp” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The MSP method detects only methylation of full-length CpG islands and cannot identify partial methylation of the promoters.

  • A number of studies have evaluated possible associations between a polymorphism in the cytochrome P450c17α ( CYP17 ) gene and breast cancer risk [ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 ] . Cytochrome P450c17α functions at key branch points in human steroidogenesis, catalyzing the ovarian and adrenal biosynthesis pathways for androstenedione, the immediate precursor of testosterone [ 17 ] . Three polymorphisms have been described in this gene: a C → T transition at nucleotide 5471 in intron 6 [ 18 ] , a G → A transition at nucleotide 47 in the 5'-untranslated region promoter [ 19 ] , and a thymidine substitution for cytosine at nucleotide 27 in the 5'-untranslated region promoter that creates a Msp AI recognition site [ 20 ] .

  • Interestingly, MGMT gene was also down regulated in 14 of the 15 tumors that did not exhibit methylation by MSP analysis.

  • The Msp AI polymorphism gives rise to three genotypes (A1/A1, A1/A2, and A2/A2).

  • Author 1 (GN) performed cell culture, MSP and gene expression analysis.


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