Words similar to momulv
Example sentences for: momulv
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This was not true for clonal or polyclonal transductants that expressed Tag from the MoMuLV LTR, which supports a high level of expression (unpublished observations).
We have previously characterized clonal mouse astrocyte cell lines, immortalized by transduction of SV40 large T antigen expressed from the MoMuLV LTR [ 6 13 ] . Here, we compare variation in Tag levels in 3 of these lines and 3 additional lines (termed tkT lines), immortalized with Moloney Sarcoma Virus vectors expressing Tag from an internal herpes thymidine kinase (tk) promoter.
IGFR, [ 29 ] ], and one study used several cell lines and demonstrated distinct effects of the cell genetic background [ 25 ] . Down-regulated genes include bFGF, FGF-2, Topoisomerase II-α, EGFR,, human HDAC1, as well as cell cycle regulatory genes among others [ 30 31 32 33 34 35 36 37 ] . Regions in the bFGF promoter have been identified as associated with density-dependent down-regulation of bFGF [ 31 ] . The IGF-II P3 promoter is down-regulated as a function of cell density, and a 7-base pair sequence has been identified that plays a critical role in this down-regulation [ 32 ] . Neither the MoMuLV LTR or the htk promoters encode this sequence, although both encode a 10-base pair sequence that is identical to the P3 sequence with an insertion of 3 base pairs at position -1081.