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Example sentences for: molegos

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The extensive contacts that APE1 makes to these positions are mediated by molegos it does not share with DNase 1. Molegos 6, 7a and 10 all have residues within hydrogen bonding distance of the three basepairs 3' of the AP-site.
Our analysis identified 5 molegos that are common to the DNase 1, IPP and APE families, which roughly correspond to areas of sequence similarity identified previously [ 31 32 ] . The structural similarities of molegos 1,2, 7, 11 and 12 (i.e.
Using molegos to detect structural and functional homologues
These molegos could in turn be functionally annotated by comparing the DNA binding profile of APE1 with that of the less specific nuclease DNase 1. This analysis indicated that residues binding 3' to the site of phosphorolytic cleavage control the substrate specificity of APE1.
The 12 conserved molegos form the β-barrel core of huAPE1.