Words similar to molegos
Example sentences for: molegos
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Molegos 4 and 9 contain no residues in contact with the DNA or metal ion.
The contact plots of APE1 and DNase1 with their respective substrates (Figure 6) documents that the similar molegos in the proteins serve similar functions.
These results indicate that molegos can provide a useful basis for identifying specificity determining regions in enzymes with similar active sites but different activity spectra [ 46 28 3 ] . Site directed mutagenesis based on these results can define the function of the unique elements of the APEs, and aid in the design of enzymes with altered specificity.
NO analyzed the structural properties of the molegos, and prepared figures 2, 3, 4, 5, 6, 7. TI prepared mutants of human APE1 protein to test the conclusions of this paper, and he provided background and list of mutations affecting APE function.
These shared motifs had a similar 3D structure in representatives of these functionally diverse families, and we therefore called these motifs "molegos" (molecular legos).
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