Example sentences for: molego

How can you use “molego” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Crystal structure data, coupled with molego analysis, outlined the areas of APE1 that distinguish its mode of DNA binding from the less specific DNase 1. Contact maps (Figure 6) illustrate how the conserved motifs direct DNA binding in the distributive (i.e.

  • CHS developed the molego concept, performed the sequence analysis and prepared the manuscript.

  • Of the four protein areas that bind to the DNA 3' of the abasic site, mutating F266 (molego 10) or W280 (middle of molego 11) decreases APE activity [ 33 ] . The F266 mutation is particularly interesting, as the mutants at this position had reduced substrate specificity and enhanced 3'-exonuclease activity.

  • Molego analysis could be useful to analyze the significance of such findings.

  • Processivity is an important facit of the activity of enzymes that function in complex pathways [ 43 ] . Reduced processivity may explain, for example, the repair deficits in Xeroderma pigmentosum (XPA) cells [ 44 ] . Our molego approach provides a basis for exploring the role of segments of the protein in its functions, rather than relying only on data from missense mutations.


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