Example sentences for: mlh

How can you use “mlh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To examine the biological role of promoter methylation in CC, we assessed the levels of mRNA by semi-quantitative RT-PCR in eight cell lines and compared with the respective control values obtained from the averages calculated from 2 normal cervix after normalization against ACTB . This analysis was performed on 7 genes ( CDH1 , DAPK , RARB , HIC1 , MGMT , RASSF1A , and MLH1 ) that exhibited methylation in one or more cell lines and primary tumors (Fig.

  • We examined the status of promoter hypermethylation of 16 genes ( CDH1 , DAPK , RARB , HIC1 , FHIT , RASSF1A , APC , CDKN2A , MGMT , BRCA1 , TP73 , TIMP3 , GSTP1 , MLH1 , p14 ARF , and RB1 ) in eight specimens of normal cervical squamous epithelia and 90 CC specimens.

  • 6%; APC , 9.8%; RARB , 7.6%; CDH1 , 7.6%; FHIT , 6.5%, MLH1 , 4.3%; TIMP3 , 3.3%; GSTP1 , 1.1%; and NME2 , 1.1% (Fig.

  • MLH1 gene was methylated in one cell line (SW756) but we found no evidence of down-regulated expression in this cell line (data not shown).

  • The primers used for amplification of methylated and unmethylated promoters of genes RARB , TIMP3 , CDKN2A , p14 ARF , MGMT , DAPK , CDH1 , GSTP1 , APC promoter 1A, RB1 , MLH1 , TP73 , BRCA1 , FHIT , and HIC1 have been described previously http://pathology2.jhu.edu/pancreas/prim0425.htm#MSP; [ 32 47 48 49 ] . Methylated (MF and MR) and unmethylated (UF and UR) primers for RASSF1A promoter were designed according to Herman et al [ 46 ] and as described earlier [ 50 ] . PCR products were run on 2% agarose gels and visualized after ethidium bromide staining.


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