Words similar to misoriented

Example sentences for: misoriented

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For the substantial subset of UniGene clusters for which the dominant transcriptional orientation was unannotated, we required that the misoriented ESTs be significantly overrepresented regardless of the correct orientation of the cluster.
Statistically significant overrepresentation of misoriented ESTs in a subset of UniGene clusters
We first identified EST libraries that were directionally cloned and sequenced (that is, ESTs were cloned and sequenced in a defined orientation with respect to the mRNA transcript); then, focusing exclusively on ESTs from such libraries, we searched for UniGene clusters containing a statistically significant number of misoriented ESTs.
Our null hypothesis was that the relatively small fraction of misoriented ESTs from high-quality directionally cloned EST libraries (approximately 1.5%) represented random artifacts, leading to the expectation that they would be distributed across the full set of UniGene clusters in a manner proportional to the sizes of individual UniGene clusters.