Example sentences for: mislocalization

How can you use “mislocalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, when the genes encoding GFP-tagged Nups were crossed into these mutant backgrounds, all displayed GFP-Nup mislocalization under non-permissive conditions (Figure 7and data not shown).

  • After 4 hours at 34°, the same conditions that cause GFP-Nup mislocalization in the other assayed sec mutants, the GFP-Nups in sec6-4 remained localized to the NPC in the characteristic, punctate NE rim pattern (Figure 7).

  • For example, replacing the 3' UTR of the mRNA for the intermediate filament protein, vimentin, with the β-actin 3'UTR sequence results in mislocalization of vimentin transcript, altered fibroblast morphology, and impaired motility [ 15 ] .

  • The mutants displaying the strongest GFP-Nup mislocalization phenotypes were backcrossed.

  • The accumulation of non-secreted protein in mutants defective in ER to Golgi transport leads to proliferation of the ER [ 37 44 ] . The membrane proliferation seen by TEM in npa1-1/sec23 and npa2-1/sec13 cells (Figure 4) and the coincident mislocalization of Nups (Figure 3and data not shown) prompted us to test if Nups were accumulating at the ER.


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