Words similar to mislocalization

Example sentences for: mislocalization

How can you use “mislocalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

The accumulation of non-secreted protein in mutants defective in ER to Golgi transport leads to proliferation of the ER [ 37 44 ] . The membrane proliferation seen by TEM in npa1-1/sec23 and npa2-1/sec13 cells (Figure 4) and the coincident mislocalization of Nups (Figure 3and data not shown) prompted us to test if Nups were accumulating at the ER.
The ts phenotype was not, however, accompanied by mislocalization of GFP-Nups after growth for 6 hours at 37°.
This further suggested that the GFP-Nup mislocalization and TEM membrane proliferation were the consequence of the same process.
Three morphological classes include sec mutants with extended networks of ER membrane, those with accumulated Golgi, and a third with accumulated 80-100 nm secretory vesicles [ 37 ] . The morphological perturbations directly correlate with distinct secretory pathway blocks: ER-Golgi, intra-Golgi, and Golgi-plasma membrane [ 44 ] . A recent study in S. pombe has also shown that sec mutants can affect NE and cell cycle progression [ 55 ] . In addition to sec13 , our screen also identified mutant alleles of SEC23 , SEC27 and BET3 . The mislocalization of GFP-Nups in sec13 and sec23 mutants was coincident with the formation of extensive honeycomb networks of ER.
The mutants displaying the strongest GFP-Nup mislocalization phenotypes were backcrossed.