Words similar to mislocalization
Example sentences for: mislocalization
How can you use “mislocalization” in a sentence? Here are some example sentences to help you improve your vocabulary:
The two largest were allelic with SEC23 and SEC13 , genes encoding known mediators of vesicular trafficking between the ER and Golgi [ 39 ] . The GFP-Nup mislocalization defects in the sec23 ( npa1 ) and sec13 ( npa2 ) mutants correlated with distinct ER membrane perturbations.
Given that the formation of the extensive membrane networks in the sec13 and sec23 mutants was coincident with the GFP-Nup mislocalization, we favor one of the two indirect models.
The release of Cdc14 from nucleolar Net1 promotes mitotic exit [ 15 17 18 ] . net1 tab 2-1cells display a panel of nucleolar defects including reduction of nucleolar silencing, mislocalization of nucleolar antigens, alteration of rDNA morphology, and reduction of rRNA synthesis [ 16 18 ] . To test whether perturbation of nucleolar structure is consistently associated with bypass of cdc15Δ, we immunolocalized the nucleolar antigen Nop1 in all tab mutants.
As cooperativity is difficult to invoke in this system, we consider that for Asw to titrate Hint enzyme activity by heterodimerization, Asw must carry a signal for mislocalization and/or proteolysis, and/or somehow alter the Hint active site.
Interestingly, mutant alleles in the two largest complementation groups showed a similar pattern of GFP-Nup mislocalization.