Example sentences for: mislocalization

How can you use “mislocalization” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The two largest were allelic with SEC23 and SEC13 , genes encoding known mediators of vesicular trafficking between the ER and Golgi [ 39 ] . The GFP-Nup mislocalization defects in the sec23 ( npa1 ) and sec13 ( npa2 ) mutants correlated with distinct ER membrane perturbations.

  • Given that the formation of the extensive membrane networks in the sec13 and sec23 mutants was coincident with the GFP-Nup mislocalization, we favor one of the two indirect models.

  • The release of Cdc14 from nucleolar Net1 promotes mitotic exit [ 15 17 18 ] . net1 tab 2-1cells display a panel of nucleolar defects including reduction of nucleolar silencing, mislocalization of nucleolar antigens, alteration of rDNA morphology, and reduction of rRNA synthesis [ 16 18 ] . To test whether perturbation of nucleolar structure is consistently associated with bypass of cdc15Δ, we immunolocalized the nucleolar antigen Nop1 in all tab mutants.

  • As cooperativity is difficult to invoke in this system, we consider that for Asw to titrate Hint enzyme activity by heterodimerization, Asw must carry a signal for mislocalization and/or proteolysis, and/or somehow alter the Hint active site.

  • Interestingly, mutant alleles in the two largest complementation groups showed a similar pattern of GFP-Nup mislocalization.


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