Words similar to mirseeker

Example sentences for: mirseeker

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A total of 42 novel candidates in the top 208 miRseeker predictions were supported by additional evidence of sequence and structural conservation in a third species (primarily Anopheles and Apis , with a smaller fraction in nematodes or vertebrates).
To allow public access to miRseeker, we developed a scaled-down version of our computational pipeline [ 58 ] . It allows a user to input two sets of homologous sequences (up to 100 kb) from any two species along with gene annotation for one of them, and performs all the steps of the miRNA-finding procedure described above, producing a list of miRNA candidates ordered by score.
Conservation alone is an insufficient criterion for assessing the validity of a miRNA [ 46 ] . Indeed, one high-scoring candidate (number 78, 2L:13233310 that is strongly conserved in Anopheles and was identified by miRseeker appears to be an unannotated U2 snRNA [ 43 ] . Nevertheless, our high success rate (20/27) leads us to believe that failure to observe expression of a high-scoring, third-species-conserved miRseeker candidate could reflect a false-negative result.
A unique aspect of miRseeker amongst the recently described methodologies is its assessment of the pattern of nucleotide divergence within miRNA precursors.
The miRseeker output data