Words similar to mirseeker

Example sentences for: mirseeker

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Despite these potential sources of error, the robust ability of miRseeker to identify genuine miRNAs is clearly indicated by its ability to identify most of the previously known Drosophila miRNAs as very high-scoring candidates and by our experimental validation of a very large number of newly identified candidate miRNA genes.
Unexpectedly, the Anopheles genome contains only four members of this subfamily, and all are located in a single cluster on 2L (Figure 7b); the same four members were identifiable in the unassembled genomic sequence of Apis [ 48 ] . The simplest scenario is that members of the K box-family have undergone radical duplication and dispersal about the genome in Drosophila . This is consistent with the finding that the remaining members of the K-box family [ 47 ] , including mir-11 , the three mir-6 paralogs and the K-box-antisense gene mir-5 , are similarly absent from both Anopheles and Apis . However, one new putative member of the K-box family (2R:4681879) was identified by miRseeker, and it has been conserved in all four sequenced insect genomes.
miRseeker public interface
the miRseeker output data, including the folded structures and evaluation of the top 208 miRseeker candidates,
miRseeker subjects conserved intronic and intergenic sequences to an RNA folding and evaluation procedure to identify evolutionarily constrained hairpin structures with features characteristic of known miRNAs.