Words similar to microspikes

Example sentences for: microspikes

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There is a possibility that the appearance of microspikes around the cells under stressed conditions is an adapted behavior of the cells in order to attach to the substratum firmly.
HGF/SF induces mitogenic and morphogenic changes, including rapid membrane ruffling, formation of microspikes, and increased cellular motility [ 12 13 ] . The diverse biological effects of HGF/SF are all mediated by Met, which is preferentially expressed on epithelial cells [ 14 ] . In vivo this receptor-ligand pair is essential for normal embryonic development [ 15 16 ] . Whereas Met signaling clearly has a role in normal cellular processes, this signaling pathway has also been implicated in tumor development and progression.
A detailed study of microspikes by Adams indicated that these structures consist of actin, the actin binding protein, 55 kd/fascin and myosin [ 40 ] . The perinuclear staining and microspikes of cells under oxidative stress in this study are very similar to those observed by Huot et al.
Filopodia formation of short filamentous actin microspikes gives way to membrane ruffling and lamellipodia formation, culminating in the organized production of actin stress fibers.
The C3 induced extensions were rich in filamentous actin, and C3 treated HPB-ALL cell bodies apparently lacked filopodial actin microspikes, present in normal spreading cells.