Words similar to microsomes
Example sentences for: microsomes
How can you use “microsomes” in a sentence? Here are some example sentences to help you improve your vocabulary:
Firstly, Go and others [ 5 6 ] showed that mefloquine alters calcium flux into and out of isolated mammalian microsomes obtained from skeletal muscle and neuronal tissue.
The incorporation of fatty acids into the mitochondria and microsomes of colon, liver and tumor was determined in mice which consumed each diet.
It would be tempting to speculate that, because mefloquine's effects on rat neuronal ER calcium homeostasis were more potent than that for dog-brain microsomes, there might exist a species difference in sensitivity to the drug.
The effects of mefloquine on ER calcium homeostasis have been examined previously [ 5 6 ] . In experiments with isolated rabbit skeletal muscle microsomes, mefloquine was found to inhibit the uptake of calcium, with an IC 50 of approximately 43 μM [ 6 ] . This effect was exacerbated by treatment with thapsigargin, a specific inhibitor of the ER calcium pump [ 6 ] . Further, the rate of ATP hydrolysis by the ER Ca 2+-ATPase was reduced in the presence of mefloquine (Ki of = 53 μM).
Total microsomes were washed twice with 0.6 M KCl buffer and 100 μg of total membrane protein was applied to a 5-15% SDS polyacrylamide gel.