Words similar to microbicides
Example sentences for: microbicides
How can you use “microbicides” in a sentence? Here are some example sentences to help you improve your vocabulary:
This includes the design and application of safe and effective topical microbicides.
Among anionic polymers considered as topical microbicides to prevent sexual transmission of HIV-1 {Carbomer 974P/BufferGel, carrageenan, CAP, cellulose sulfate, dextran/dextrin sulfate, poly(napthalene sulfonate) and poly(styrene-4-sulfonate)}, CAP formulated in a micronized form, is the only compound which has a capacity to remove from physiological fluids infectious virus by adsorption onto the micronized particles.
To the best of our knowledge, results reported here and earlier [ 8 ] represent the most detailed study on the mechanism of action of a polymeric anti-HIV-1 compound and offer new opportunities for microbicide research, including the design of combined microbicides with distinct target sites on HIV-1 and acting synergistically.
Consideration of these side effects might contribute to the process of selection of preferred microbicides for future large-scale use.
Such activity was reported for dextran sulfate after 2 h incubation with HIV-1 [ 2 ] but results of other studies indicated that dextran sulfate failed to neutralize virus infectivity [ 4 10 ] . Inactivation of HIV-1 by carrageenan was reported in a review article [ 18 ] . BufferGel is virucidal against HIV-1 by providing a buffered low pH environment (pH 3.9 [ 25 ] ), but virus inactivation might be incomplete and possibly compromised by minor pH increases due to the presence of seminal fluid [ 40 ] . To be effective in preventing infection by direct virus inactivation, anti-HIV-1 microbicides must be virucidal against both X4 and R5 viruses, utilizing CXCR4 and CCR5 as coreceptors [ 39 41 ] , respectively, R5 HIV-1 being most frequently sexually transmitted.
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