Example sentences for: microbicides

How can you use “microbicides” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 3), it was of interest to determine whether anionic polymeric candidate microbicides in soluble form at neutral pH would have similar effects.

  • This includes the design and application of safe and effective topical microbicides.

  • Such activity was reported for dextran sulfate after 2 h incubation with HIV-1 [ 2 ] but results of other studies indicated that dextran sulfate failed to neutralize virus infectivity [ 4 10 ] . Inactivation of HIV-1 by carrageenan was reported in a review article [ 18 ] . BufferGel is virucidal against HIV-1 by providing a buffered low pH environment (pH 3.9 [ 25 ] ), but virus inactivation might be incomplete and possibly compromised by minor pH increases due to the presence of seminal fluid [ 40 ] . To be effective in preventing infection by direct virus inactivation, anti-HIV-1 microbicides must be virucidal against both X4 and R5 viruses, utilizing CXCR4 and CCR5 as coreceptors [ 39 41 ] , respectively, R5 HIV-1 being most frequently sexually transmitted.

  • Consideration of these side effects might contribute to the process of selection of preferred microbicides for future large-scale use.

  • Induction of six-helix bundle formation by polymeric anionic candidate microbicides


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