Words similar to microbicides
Example sentences for: microbicides
How can you use “microbicides” in a sentence? Here are some example sentences to help you improve your vocabulary:
Such activity was reported for dextran sulfate after 2 h incubation with HIV-1 [ 2 ] but results of other studies indicated that dextran sulfate failed to neutralize virus infectivity [ 4 10 ] . Inactivation of HIV-1 by carrageenan was reported in a review article [ 18 ] . BufferGel is virucidal against HIV-1 by providing a buffered low pH environment (pH 3.9 [ 25 ] ), but virus inactivation might be incomplete and possibly compromised by minor pH increases due to the presence of seminal fluid [ 40 ] . To be effective in preventing infection by direct virus inactivation, anti-HIV-1 microbicides must be virucidal against both X4 and R5 viruses, utilizing CXCR4 and CCR5 as coreceptors [ 39 41 ] , respectively, R5 HIV-1 being most frequently sexually transmitted.
Induction of six-helix bundle formation by polymeric anionic candidate microbicides
Negatively charged sulfated polymers were reported to have anti-HIV-1 activity and are being considered for development as topical microbicides.
This includes the design and application of safe and effective topical microbicides.
To the best of our knowledge, results reported here and earlier [ 8 ] represent the most detailed study on the mechanism of action of a polymeric anti-HIV-1 compound and offer new opportunities for microbicide research, including the design of combined microbicides with distinct target sites on HIV-1 and acting synergistically.
Loading...