Example sentences for: microbicide

How can you use “microbicide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Effect of anionic polymeric microbicide candidates on the integrity of HIV-1 particles

  • Since heparin and other anionic polymers are known to inhibit blood clotting [ 55 ] , the effect of anionic polymeric microbicide candidates on blood clotting was measured.

  • To avoid this, CAP in micronized form (which does not aggregate at low pH), instead of CAP in soluble form is being considered as a topical microbicide [ 30 31 32 33 34 35 ] . Micronized CAP (Aquateric) was shown to be virucidal against HIV-1, herpesviruses and several nonviral sexually transmitted disease (STD) pathogens [ 30 31 32 33 34 ] . The virucidal activity of micronized CAP could at least partly be explained by its buffering capacity at low pH [ 40 ] since it is a free acid while other anionic polymeric microbicide candidates (except BufferGel, the active ingredient of which is Carbomer 974P [ 27 ] ) are sodium salts.

  • To the best of our knowledge, results reported here and earlier [ 8 ] represent the most detailed study on the mechanism of action of a polymeric anti-HIV-1 compound and offer new opportunities for microbicide research, including the design of combined microbicides with distinct target sites on HIV-1 and acting synergistically.

  • The answers to these questions would greatly enhance our understanding of HIV transmission and pathogenesis, and thus would provide further guidance toward an effective vaccine or microbicide.


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