Words similar to mfs

Example sentences for: mfs

How can you use “mfs” in a sentence? Here are some example sentences to help you improve your vocabulary:

For example, exon-skipping mutations in the central region of the gene, exons 24-32, cause severe phenotypes or neonatal presentations [ 8 ] . But there are exceptions, only four of the many other mutations in this region cause severe phenotypes, while one mutation predicted to lead to skipping of exon 24 was found in a patient with classic MFS [ 5 ] . In contrast, most cysteine substitutions cause classic MFS with a high frequency of lens dislocation, although some patients in our study did not meet the Ghent criteria for diagnosis of MFS [ 9 ] . Amino-acid substitutions not disrupting disulfide bonds may be associated with fibrillinopathies other than MFS, although mutations in the calcium-binding consensus sequence have been reported in individuals with classic MFS [ 5 10 11 12 ] . It is clear from the studies reported so far, that genotype-phenotype correlations are not straight-forward for FBN1 mutations.
De novo deletion of three cbEGF-like domains encoded by exons 44-46 resulted in a severe form of MFS diagnosed in infancy.
A total of 60 patients were screened with this method, 55 of which met diagnostic criteria for MFS and 5 had partial manifestations.
Partial deletion of an 8-cysteine (LTBP-like) domain and loss of the downstream 6-cysteine calcium-binding (cb) epidermal growth factor (EGF)-like domain caused protein instability and classic MFS.
There was no family history of MFS, both parents were deceased.