Words similar to metaphase
Example sentences for: metaphase
How can you use “metaphase” in a sentence? Here are some example sentences to help you improve your vocabulary:
Chromosome cohesion is established during S phase (when the chromosomes are replicated) and is then dissolved completely in metaphase to allow sister chromatids to come apart.
Based on this arrangement and the sequence of the adjacent neck domain, we assigned KIF27 to the N-5 phyogenetic group of kinesins [ 27 ] . The N-5 subgroup is defined by the human KIF4 protein, which is primarily localized to the nuclear matrix and associates with chromosomes during mitosis [ 35 ] . In cell division, nuclear kinesins of this chromokinesin class appear to be important for the maintenance of sister chromatids on the metaphase plate [ 36 ] . However, additional functions for nuclear kinesins have recently been uncovered.
Chromosome analyses of GTG banded metaphase cells at a 400 band level minimum resolution were performed on one or more affected family members of each family whenever possible to rule out cytogenetic abnormalities.
Intriguingly, HSP90 staining was primarily localized to the microvillar region of normal eggs (the region opposite the pole containing the metaphase chromatin) whereas the staining became delocalized and more intense following activation.
In another report, micro-injection of PP1 decreased extractability of pRB from nuclei, presumably by increasing dephosphorylation and increasing association with nuclear proteins thereby playing a role in G1/S transition inhibition [ 13 ] . Micro-injection of antibodies to the PP1 catalytic subunit has been shown to block cells in metaphase [ 23 ] . Since this is the time during mitosis when pRB is normally dephosphorylated [ 11 24 ] , it is tempting to speculate that prevention of pRB dephosphorylation by inhibiting PP1 activity impedes an orderly progression through mitosis, perhaps contributing towards a transformed phenotype.
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