Example sentences for: metaphase

How can you use “metaphase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To localize MADS-IX cytologically, we labeled the 2 kb sized MADS-IX with Spectrum Green (Vysis) and hybridized on normal human metaphase chromosomes.

  • The probe mixtures were then applied to rat fibroblast metaphase chromosome slides (previously denatured at 73°C for 2 min in 70 % formamide, 2 × SSC).

  • Based on this arrangement and the sequence of the adjacent neck domain, we assigned KIF27 to the N-5 phyogenetic group of kinesins [ 27 ] . The N-5 subgroup is defined by the human KIF4 protein, which is primarily localized to the nuclear matrix and associates with chromosomes during mitosis [ 35 ] . In cell division, nuclear kinesins of this chromokinesin class appear to be important for the maintenance of sister chromatids on the metaphase plate [ 36 ] . However, additional functions for nuclear kinesins have recently been uncovered.

  • FISH experiments were performed under standard conditions [ 34 ] . For each FISH experiment at least 20 independent metaphase chromosome preparations were examined.

  • Common agents currently used in treating metastatic breast cancer are the antimitotics paclitaxel and docetaxel [ 1 2 ] . These drugs bind to β-tubulin, a major protein in mitotic spindles, and halt cell division at metaphase.


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