Words similar to metal-coordinating
Example sentences for: metal-coordinating
How can you use “metal-coordinating” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, it appears likely that the ancestral DDRP evolved from the coalescence of at least 3 distinct domains: i) the DPBB that probably originally bound RNA and, subsequently, segregated into the cores of the β' subunit, where it acquired the metal-coordinating active site, and of the β subunit, with the two lysines projecting into the catalytic cleft (Fig.
Taken together, these observations suggest that, although RDRPs and the β' subunits of DDRPs show limited sequence similarity, these two RNA polymerase families share a homologous catalytic domain, which consists of a double-psi-β-barrel containing the metal-coordinating DbDGD motif.
We also present evidence that RDRP and the ubiquitous β' subunit of DDRP contain a homologous, metal-coordinating, catalytic domain.
This version of the DPBB domain lacks the metal-coordinating motif but contributes two lysine residues, which are critical for substrate interactions in the catalytic cleft.
One of these corresponds to the catalytic, metal-coordinating domain, containing the DbDGD motif, in the β' subunit (residues: 626-750 of pdb id:1iw7 chain D), whereas the other one corresponds to the conserved core domain of the β subunit (residues:673-994 of pdb id: 1iw7 chain C).
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