Example sentences for: mesangial

How can you use “mesangial” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Prostanoids are important regulators of fibroblast function [ 5 6 7 8 9 ] . Prostaglandin (PG)E 2 is thought to have antifibrotic properties in vitro , but also can have proinflammatory effects both in vivo and in vitro [ 10 11 12 ] . Thromboxane (TX)A 2 increases proliferation, and DNA and RNA synthesis in several cell types, including fibroblasts and smooth muscle like glomerular mesangial cells [ 13 14 15 16 ] . Conversely, prostacyclin (PGI 2 ) decreases smooth muscle cell proliferation and collagen synthesis [ 17 18 ] .

  • In contrast, in diabetic mice with albuminuria, mesangial expansion, and glomerulosclerosis, absence of CD36 expression was associated with normal appearance of the tubular epithelium and interstitial space.

  • Periodic acid–Schiff–stained sections of kidneys from mice exposed to type 2 diabetes (db/db mice) for 20 wk (Figure 2A), or type 1 diabetes (STZ-treated C57BL/6J mice) for 20 wk (data not shown) demonstrated moderate to advanced mesangial expansion and glomerulosclerosis (Figure 2A).

  • In contrast, TED and IF were associated with moderate to advanced mesangial expansion and glomerulosclerosis on kidney sections of human DNP (Figure 2B).

  • Using microarray-based gene expression profiling on whole kidney RNA together with supervised clustering methods, we previously identified and validated gene expression patterns for molecular classification of diabetic mice with albuminuria and mesangial expansion [5].


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