Words similar to mesangial
Example sentences for: mesangial
How can you use “mesangial” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the absence of SPARC, expression of transforming growth factor-β1 and type I collagen is down-regulated in kidney mesangial cells [ 15 ] . The expression of cell surface receptor for insulin-like growth factor I in SPARC-null embryonic fibroblasts is also diminished [ 16 ] . Studies with SPARC-null cells have confirmed that SPARC functions in cell proliferation.
In cultured cells RNase protection assay detected EP2 expression in renal medullary interstitial cells (MICs), while no signal was detected in cultured cortical collecting ducts or glomerular mesangial cells (Fig.
Prostanoids are important regulators of fibroblast function [ 5 6 7 8 9 ] . Prostaglandin (PG)E 2 is thought to have antifibrotic properties in vitro , but also can have proinflammatory effects both in vivo and in vitro [ 10 11 12 ] . Thromboxane (TX)A 2 increases proliferation, and DNA and RNA synthesis in several cell types, including fibroblasts and smooth muscle like glomerular mesangial cells [ 13 14 15 16 ] . Conversely, prostacyclin (PGI 2 ) decreases smooth muscle cell proliferation and collagen synthesis [ 17 18 ] .
In contrast, TED and IF were associated with moderate to advanced mesangial expansion and glomerulosclerosis on kidney sections of human DNP (Figure 2B).
Early abnormalities of DNP affect glomeruli and include an increase in glomerular filtration rate, microalbuminuria, glomerular hypertrophy, and thickening of the glomerular basement membrane, followed by expansion of mesangial extracellular matrix and glomerulosclerosis [1,2].
Loading...