Example sentences for: melatonin

How can you use “melatonin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We used C3H/He mice because they are useful for studying clock activity based on rhythmic release of melatonin; C3H/He is one of the few mouse strains that synthesizes melatonin rhythmically [ 29, 44].

  • Perhaps the best understood is the lack of the ability to produce melatonin in some strains such as BALB/c and C57Bl/6 and the production of normal rhythms of melatonin in others such as the C3H/He and CBA [ 44, 46, 47, 48, 49].

  • However, recent work shows that laboratory rat strains vary in their responsiveness to photoperiod [ 3 4 5 6 ] . Laboratory rats of some strains can be manipulated to unmask responses to photoperiod or melatonin, even though short photoperiod alone does not affect reproduction [ 7 8 9 ] . Peripubertal rats in the inbred Fischer 344 (F344) and Brown Norway (BN) strains are naturally sensitive to reproductive inhibition by short photoperiod alone [ 4 5 6 ] . In several species of rodents, peripubertal young have stronger reproductive responses to photoperiod than adults [ 10 11 12 13 ] , and this appears to be true for induced-photoresponsive laboratory rats as well [ 14 ] .

  • Previous work demonstrated that young F344 rats have a period of photoresponsiveness that delays reproductive maturation, reduces food intake, and slows somatic growth [ 5 15 ] , and that these responses are pineal and melatonin dependent [ 5 16 ] . This study demonstrates that F344 rats are also photoresponsive as adults (Figs.

  • However, widespread expression and rhythmic regulation of mNoc argues against a limited role in rhythmic physiology of the retina or in the regulation of its melatonin output rhythm suggested by the earlier work on the Xenopus eye.


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