Words similar to melanocytic
Example sentences for: melanocytic
How can you use “melanocytic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our finding that TYRP-1 is also expressed in the poorly metastatic or noninvasive cell lines NM-2C5 [ 2 ] , T47D, MCF7 and DU145 [ 5 ] , which are derived from human breast cancers and prostate tumors that are nonmetastatic, indicates that this molecule is not exclusively expressed in cells of the melanocytic lineage.
Although, these melanocytic capsular nevi appear benign morphologically, a low probability that they may represent subtle metastases was also considered.
As compared to this, none of the 81 slices of sentinel lymph nodes from 30 cases of mammary carcinoma showed capsular melanocytic nevi.
Hypothetically, an association between the higher prevalence of melanocytic capsular nevi and the predisposition for melanoma may be likely.
Clinically, TYRP-1 is thought to be important as a melanoma antigen that is highly antigenic to cytotoxic T cells, providing a potential target for melanoma vaccine development [ 16 ] . TYRP-1 appears to be less expressed in advanced primary lesions and metastases of human cutaneous melanoma and uveal melanoma [ 32 ] . Primary melanoma samples express TYRP-1 transcripts at higher levels than melanoma metastases [ 33 ] , and IHC analysis of malignant melanocytic lesions has shown that the invasive cells of primary melanomas are TYRP-1-negative [ 34 ] .