Example sentences for: melanocortin

How can you use “melanocortin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, factors that regulate hypothalamic melanocortin tone are not fully elucidated.

  • 1Band 1C) as well as melanocortin tone (Fig.

  • Reduction in hypothalamic melanocortin tone, caused by reduction in proopiomelanocortin (POMC) mRNA and elevation in agouti-related peptide (AGRP) mRNA, is thought to play a key role in mediating nutritional effects on neuroendocrine function [ 1 2 ] . Thus fasting [ 3 4 ] , insulin deficiency [ 5 ] , and leptin deficiency [ 4 ] are all associated with reduced hypothalamic melanocortin tone.

  • concerning NPY [ 14 ] , and suggesting that increases in corticosterone mediate fasting-induced changes in melanocortin tone.

  • Although a reduction in plasma leptin plays an important role in mediating neuroendocrine responses to fasting [ 6 ] and diabetes [ 17 ] , we have previously demonstrated that fasting can regulate hypothalamic melanocortin tone independently of both leptin and insulin [ 5 ] . The present studies suggest that corticosterone may play a role in mediating these leptin-independent effects.


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