Words similar to melanocortin
Example sentences for: melanocortin
How can you use “melanocortin” in a sentence? Here are some example sentences to help you improve your vocabulary:
3A), and serum insulin, leptin and melanocortin tone were also reduced in this condition (Fig.
[ 14 ] . These data suggest that leptin's effect to reverse effects of fasting on melanocortin tone may require and be mediated by a reduction in glucocorticoids.
Reduction in hypothalamic melanocortin tone, caused by reduction in proopiomelanocortin (POMC) mRNA and elevation in agouti-related peptide (AGRP) mRNA, is thought to play a key role in mediating nutritional effects on neuroendocrine function [ 1 2 ] . Thus fasting [ 3 4 ] , insulin deficiency [ 5 ] , and leptin deficiency [ 4 ] are all associated with reduced hypothalamic melanocortin tone.
concerning NPY [ 14 ] , and suggesting that increases in corticosterone mediate fasting-induced changes in melanocortin tone.
After more chronic exposure, this delicate balance could plausibly become disrupted, leading to glucocorticoid-mediated development of the metabolic syndrome [ 10 ] . Thus interactions between insulin, leptin, and glucocorticoids, and the neuropeptide responses they generate within the melanocortin system, allow complex metabolic responses to nutritional status but may also allow the development of metabolic pathologies.
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