Words similar to medulloblastomas

Example sentences for: medulloblastomas

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Affected individuals develop a large spectrum of CNS and extra-CNS neoplasms, including medulloblastomas [ 2 ] . Interestingly, alterations in p53 are relatively rare in sporadic medulloblastomas, with mutations detected in 5% or less of cases [ 3 4 ] .
Literature profiles were generated for a second large dataset consisting of the 200 genes and ESTs found to be the most differentially regulated in classic versus desmoplastic medulloblastomas in a study of central nervous system tumors [ 19].
The greatly increased incidence of medulloblastomas in patients inheriting mutations in the APC tumor suppressor gene suggests that activation of Wnt signaling could be sufficient in some cases to initiate medulloblastoma formation.
We have previously shown that nuclear β-catenin is present in 18% of sporadic medulloblastomas [ 18 ] .
In order to determine if Wnt signaling was aberrantly active in the cerebellar neuroblasts thought to give rise to some medulloblastomas, β-catenin immunostains were performed on newborn Mut-1 and Mut-2 animals.