Words similar to medulloblastomas
Example sentences for: medulloblastomas
How can you use “medulloblastomas” in a sentence? Here are some example sentences to help you improve your vocabulary:
The greatly increased incidence of medulloblastomas in patients inheriting mutations in the APC tumor suppressor gene suggests that activation of Wnt signaling could be sufficient in some cases to initiate medulloblastoma formation.
In man, three inherited syndromes associated with medulloblastomas have been described: Turcot's, Gorlin's and Li Fraumeni (reviewed in [ 1 ] ). Li Fraumeni syndrome is caused by inherited mutations in the p53 tumor suppressor gene.
We have previously shown that nuclear β-catenin is present in 18% of sporadic medulloblastomas [ 18 ] .
Mice heterozygous for PTCH and lacking p53 all developed medulloblastomas by 3 months of age [ 12 ] .
Literature profiles were generated for a second large dataset consisting of the 200 genes and ESTs found to be the most differentially regulated in classic versus desmoplastic medulloblastomas in a study of central nervous system tumors [ 19].