Words similar to medulloblastomas

Example sentences for: medulloblastomas

How can you use “medulloblastomas” in a sentence? Here are some example sentences to help you improve your vocabulary:

Mice heterozygous for PTCH and lacking p53 all developed medulloblastomas by 3 months of age [ 12 ] .
We have previously shown that nuclear β-catenin is present in 18% of sporadic medulloblastomas [ 18 ] .
Affected individuals develop a large spectrum of CNS and extra-CNS neoplasms, including medulloblastomas [ 2 ] . Interestingly, alterations in p53 are relatively rare in sporadic medulloblastomas, with mutations detected in 5% or less of cases [ 3 4 ] .
Mutations in the Hedgehog pathway members PTCH , PTCH 2 , SUFU and Smo , have all been identified in sporadic medulloblastomas as well, with approximately 25% of cases containing mutations affecting these genes [ 5 6 7 8 9 ] . A murine medulloblastoma model was recently developed by disruption of the PTCH gene, with medulloblastoma-like tumors arising in 10-15% of heterozygotes by 9 months of age [ 10 11 ] . Breeding PTCH mice to p53 knockout animals markedly increased tumor incidence.
In order to determine if Wnt signaling was aberrantly active in the cerebellar neuroblasts thought to give rise to some medulloblastomas, β-catenin immunostains were performed on newborn Mut-1 and Mut-2 animals.