Example sentences for: mechanism

How can you use “mechanism” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Aside from its well-characterized role in protein folding [ 66 ] , Hsp70 is known to associate with the GR in the cytoplasm, where it promotes formation of a heterocomplex between the inactive GR and Hsp90 [ 67 ] . In addition, Hsp70 becomes concentrated in the nucleus when cells are exposed to environmental stress [ 68 ] . Of particular note, the nuclear accumulation of the Hsp70, Ssa4p, in response to nutrient deprivation in yeast appears to occur by a novel mechanism that involves its direct interaction with Mmd5p, a member of the importin-β family [ 69 ] . A role for Rab24 in nuclear trafficking would be unanticipated, since the only GTPase known to function in nuclear import/export (Ran) is structurally distinct from the Rab subgroup of the Ras superfamily [ 70 71 ] . Nevertheless, we can speculate that if Rab24 participates in a stress-induced pathway for nuclear import of Hsp70 in mammalian cells, the constitutive overexpression of Rab24(D123I) might stimulate aberrant accumulation of Hsp70/importin-β aggregates at the nuclear pore complex.

  • Further, based on the tissue specific effects of cry b it is possible that the configuration of a clock mechanism may vary between different cell types.

  • Transgene PTGS thus tapped into a preexisting natural mechanism for combating viruses.

  • We took a discovery-driven approach to study the signaling mechanism of Smad1, by systematically searching for proteins that can physically interact with Smad1.

  • Together, these data indicate that RSV infection of A549 epithelial cells induces chemokine expression with distinct kinetics suggesting the mechanism of RSV induction differs from that of proinflammatory cytokines.


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