Example sentences for: mcp-
How can you use “mcp-” in a sentence? Here are some example sentences to help you improve your vocabulary:
IL (Interleukin), LPS (Lipopolysaccharides), MCP-1 (Monocyte chemoattractant protein-1), MGBE (Mouse gallbladder epithelial cells), MIP-2 (Macrophage inflammatory protein-2), RANTES (Regulated on activation, normal T cell expressed and secreted), TNF-α (Tumor Necrosis Factor-alpha).
In addition to MCP-1, IL-8 and MGSA have also been evaluated for production of collagen [ 46 ] . These investigators reported that treatment of normal fibroblasts with these chemokines did not affect collagen levels.
While most cytokine research has focused on cells of the immune system, other cell types produce cytokines including the epithelial cells of the lung [ 28 29 ] , retina [ 30 ] , and intestines [ 31 32 ] . Among the few studies involving the biliary system, it was demonstrated that cultured human intrahepatic duct epithelial cells produce functional IL-8 and MCP-1 (CCL2) [ 14 33 ] . Isolated human intrahepatic epithelial ducts expressed immunoreactive IL-6 when treated with IL-1β or phorbal myristate acetate [ 34 ] . Intracellular TNF-α mRNA and protein was detected in intrahepatic biliary duct cells in tissue sections [ 35 ] , but not in cultured intrahepatic epithelial cells; therefore, there was no clear demonstration that biliary epithelium secretes TNF-α.
The inhibitor studies correlating chemokine gene expression and NF-κB binding activity indicate that RSV, in contrast to TNFα, induces IL-8, MCP-1 and RANTES expression in A549 epithelial cells through a redox-sensitive NF-κB signaling pathway that appears to involve predominately Rel A. IL-8, MCP-1 and RANTES are known redox regulated genes and our results are consistent with the findings that oxidant tone can regulate chemokine gene expression in RSV infected airway epithelial cells [ 46 47 48 ] .
MCP-2 and Cystatin C cDNAs contain all six restriction sites within 500 bp from the poly-A tail (experimental fragment lengths including poly-A tail and labelling oligonucleotides: MCP-2/Cystatin C: Dde I: 196.
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