Example sentences for: mcp-
How can you use “mcp-” in a sentence? Here are some example sentences to help you improve your vocabulary:
CMV = cytomegalovirus, MCMV = murine cytomegalovirus, MCP-1 = monocyte chemoattractant protein-1, PCNA = proliferating cell nuclear antigen, PDGF = platelet derived growth factor, SSc = systemic sclerosis, TGF-β 1 = transforming growth factor-β 1 , TUNEL = terminal TdT-mediated dUTP nick end labeling, α-SMA = α-smooth muscle actin
These ligands would include RANTES, MIP-1α and MCP-3 (CCR1), MCP-1, MCP-2, MCP-3, MCP-4, MCP-5 (CCR2), RANTES, MIP-1α, and MIP-1β (CCR5), IL-8 and CGP-2 (CXCR1), IL-8, GROα, and epithelial-derived neutrophil attractant 78 (CXCR2), IP-10 and MIG (CXCR3), and stromal cell derived factor-1 (CXCR4) [ 13].
The elevated expression of PDGF in our model is also significant since the expression of these growth factors by endothelial cells can be induced by direct immune cell - endothelial cell interaction, promoting smooth muscle cell migration and proliferation in atherosclerosis [ 39 ] . CMV, as well as other viruses, induces expression of a number of cytokines and growth factors in cells in vitro, including TGF-β, a profibrogenic cytokine [ 40 41 ] . MCP-1 is a member of the β-chemokine (C-C) family [ 42 ] and this chemokine has been implicated in pathogenesis of SSc [ 43 ] . Our results (Fig.
2, RSV rapidly induced IL-8 and MCP-1 with steady-state mRNA readily detected as early as 1 hr and continued to increase over the 24 hr time course.
An analysis of chemokines produced by RA SCL indicated that these cells expressed MCP-1 and IL-8 mRNAs, and also secreted MCP-1 and IL-8.
Loading...