Words similar to mcp-

Example sentences for: mcp-

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MCP-1 and IL-8 play a role in migration of monocytes
Anti-MCP-1 and anti-IL-8 mAbs decreased monocyte migration significantly, with the effect of anti-MCP-1 being consistently greater than that of anti-IL-8.
In A549 epithelial cells substantial MCP-1 was constitutively expressed whereas little or no spontaneous IL-8 or RANTES was detected.
The elevated expression of PDGF in our model is also significant since the expression of these growth factors by endothelial cells can be induced by direct immune cell - endothelial cell interaction, promoting smooth muscle cell migration and proliferation in atherosclerosis [ 39 ] . CMV, as well as other viruses, induces expression of a number of cytokines and growth factors in cells in vitro, including TGF-β, a profibrogenic cytokine [ 40 41 ] . MCP-1 is a member of the β-chemokine (C-C) family [ 42 ] and this chemokine has been implicated in pathogenesis of SSc [ 43 ] . Our results (Fig.
IL-8, MCP-1 and RANTES gene expression are regulated by the redox responsive transcription factor NF-κB [ 18 20 23 25 26 27 28 29 30 31 32 33 41 42 43 44 ] . The NF-κB signaling pathways have been shown to be differentially affected by antioxidants and glucocorticoid steroids [ 45 ] . To determine whether RSV and TNFα induction of chemokine expression might be mediated by different NF-κB signaling pathways we pretreated A549 cells with the glutathione precursor N-acetyl-L-cysteine (NAC) or the synthetic glucocorticoid dexamethasone (DEX).