Example sentences for: maximally

How can you use “maximally” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In West, Brown, and Enquist's model, the maximally efficient network that serves every part of a body has a fractal structure, showing the same geometry at different scales.

  • Cdc15, Dbf2, and Mob1 are not properly localized to the spindle pole body in a significant fraction of cdc5-1 cells [ 30 31 17 ] , and Dbf2/Mob1 protein kinase activity is diminished in cdc5 cells [ 15 16 17 ] , suggesting that at least one function of Cdc5 is to generate maximally active Dbf2/Mob1, which can then trigger Cdc14 release.

  • For example, RP L18, which was significantly down-regulated by NGF, has been reported to negatively regulate double-stranded RNA (dsRNA)-activated protein kinase (PKR) [ 45 ] . As an additional example RP S19, which is also down-regulated by NGF, has been implicated in erythropoiesis and has also been described as a monocyte chemotactic factor [ 46 ] . As one last example, rat RP L9 which we found to be up-regulated by NGF starting within a few hours and maximally by 8 hrs, has been shown to be the ortholog of the yeast gene grc5 which appears to be involved in multiple cellular functions including growth control, cytoskeleton control and energy metabolism [ 47 ] . Identification of NGF-regulated RPs should now facilitate exploration of their potential roles in the responses of cells to neurotrophins.

  • Pretreatment of RAW cells with RANKL for 48 hours rendered them resistant to IFN-γ; these mononuclear cells formed multinuclear osteoclasts despite the presence of maximally inhibitory doses of IFN-γ (10 ng/ml).

  • Time course studies of dendritic growth in neurons exposed to maximally effective concentrations of BMP-5 and BMP-7 reveal comparable temporal responses as well (Figure 3).


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