Words similar to mart-
Example sentences for: mart-
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Out of 188 slices, a pool of sections immunostained individually with MART-1 and Melan-A during our previous study (Figure 1) were compared with the cocktail.
At present histomorphologic examination with immunohistochemistry remains the most reliable and practical means of detecting melanoma micrometastases in sentinel lymph nodes [ 6 21 ] . MART-1 and Melan-A are two antibodies to different epitopes of the same antigen and are complementary to each other.
As expected, combining a monoclonal antibody to tyrosinase with MART-1 and Melan-A in the cocktail increased the spectrum to encompass three epitopes of two melanoma antigens (MART-1/Melan-A and tyrosinase).
8%–87%), and these responses were specific as they had little response to A375, a HLA-A*0201-positive melanoma cell that does not express gp100 or MART-1 and served as a negative control for antigen-specific killing (Table 1; 2.7% and 3%).
As previously reported, MART-1 and Melan-A demonstrated predominantly cytoplasmic staining of melanoma cells [ 6 ] . The monoclonal antibody (T311) to tyrosinase, has been reported to demonstrate high sensitivity and specificity for melanoma [ 13 ] . It has also demonstrated an immunostaining pattern in sentinel lymph nodes identical to MART-1 and Melan-A.
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