Example sentences for: mapks

How can you use “mapks” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To examine if CSC-upregulation of cytokine production involves activation of MAPKs we examined CSC-treated NHBEs for specific phosphorylated species.

  • To determine if ERK1 or p38 MAPKs phosphorylated RARα, some cultures were treated with 50 μM PD98059 or 10 μM SB203580 for the same time period.

  • Finally, activation of MAPKs has been shown to activate the singly spliced and unspliced (genomic) latent HIV-1 virus.

  • Previous studies have shown that the amino terminus of the estrogen receptor is phosphorylated by MAPK proteins [ 12 ] . To determine the participation of MAPKs in RARα phosphorylation, we performed RARα immunoprecipitation on SCC25 cells treated with the MEK/ERK inhibitor PD98059 or p38 inhibitory drug SB203580.

  • Cigarette smoke has been shown by others to induce a synthesis of glutathione and gamma-glutamylcysteine that was associated with transcription factor AP-1 or an AP-1-like response element [ 9 ] . Although MAPKs and NFκB have been implicated in the upregulation of proinflammatory cytokines, the role of these pathways in normal human pulmonary epithelial cells in response to CSC has not been investigated.


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