Example sentences for: mapks

How can you use “mapks” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A significant finding of this study is that MAPKs such as ERK1/2 (p44/p42) are consistently activated in NHBEs.

  • Previous studies have shown that the amino terminus of the estrogen receptor is phosphorylated by MAPK proteins [ 12 ] . To determine the participation of MAPKs in RARα phosphorylation, we performed RARα immunoprecipitation on SCC25 cells treated with the MEK/ERK inhibitor PD98059 or p38 inhibitory drug SB203580.

  • During this transition, tightly-regulated post-translational phosphorylation-dephosphorylation events and proteasome-mediated proteolytic reactions regulate the activation and inactivation of signal transduction pathways that control chromatin condensation, nuclear membrane dissolution, microtubule nucleation, and formation of a haploid oocyte [ 8 9 10 ] . Several kinases that exert major roles during OM include maturation promoting factor (MPF) [ 9 11 ] , mitogen-activated protein kinases (MAPKs) [ 12 13 ] , and the product of the c-mos protooncogene Mos kinase [ 14 15 ] . Also, during OM oocytes undergo two highly-regulated metaphase-anaphase transitions (MAT) in which homologous chromosomes are equally and randomly segregated to an oocyte and first polar body and a subsequent division in which equational division of sister chromatids results in a haploid oocyte and a second polar body.

  • To determine if ERK1 or p38 MAPKs phosphorylated RARα, some cultures were treated with 50 μM PD98059 or 10 μM SB203580 for the same time period.

  • Opioid receptors (ORs), like many other G protein-coupled receptors (GPCRs), are capable of signalling via the family of mitogen activated protein kinases (MAPKs).


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