Example sentences for: mapk

How can you use “mapk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Known activators include reactive oxygen species [ 3 4 ] , growth factors [ 5 ] , and agonists of G-protein coupled receptors [ 6 7 ] . The two other MAPK pathways, the JNK and p38 pathways, have been implicated in a variety of similar cellular functions.

  • These results indicate that a reduction in the function and density of endogenous EGFRs has little effect on opioid-mediated MAPK cascades, and suggests that the enzyme cascades that control δ-OR- and EGFR-mediated ERK activation are separate.

  • In order to prove that p44/42 MAPK can be stimulated in H441 cells by an activator of this kinase, some cells were also treated with 10 nM 12- O -tetradecanoylphorbol-13-acetate (TPA), a strong stimulator of p44/42 MAPK in H441 cells, for 5 min [ 21 ] . TPA caused an approximately twofold increase in p44/42 MAPK phosphorylation over control levels.

  • Previous studies have shown that the amino terminus of the estrogen receptor is phosphorylated by MAPK proteins [ 12 ] . To determine the participation of MAPKs in RARα phosphorylation, we performed RARα immunoprecipitation on SCC25 cells treated with the MEK/ERK inhibitor PD98059 or p38 inhibitory drug SB203580.

  • The C-terminal C-box (aa 352-399), harboring the transactivation domain, contains several consensus mitogen activated protein kinase (MAPK) phosphorylation sites.


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