Words similar to mapk
Example sentences for: mapk
How can you use “mapk” in a sentence? Here are some example sentences to help you improve your vocabulary:
In Fig 5Awe found that Btk:ER activated ERK MAPK in parental but not in PLCγ2-deficient cells (lanes 2 and 7).
However, PD98059, added alone, abolished p44/42 MAPK phosphorylation in control cells and also inhibited basal SP-A mRNA levels in a dose-dependent manner.
The results of our study implicate the ERK1/2 (p42/44) MAPK pathway as a key element in this inflammatory response, an association that has not heretofore been reported in normal human pulmonary epithelial cells.
As stated in the introduction, several GPCRs (including the EPAR, β 2 -AR, and substance P (SP-R)) [ 14 18 19 20 ] increase EGFR phosphorylation during the course of ERK activation, and it is believed, that in these instances, this event is an initial step in the progression of the MAPK cascade.
Specifically, we show that glucose stimulates CD36 cell surface expression in proximal tubular epithelial cells (PTECs), and increased CD36 renders PTECs susceptible to both AGE- and PA-induced PTEC apoptosis by mediating sequential activation of src kinase, proapoptotic p38 MAPK, and caspase 3. Based on these findings, we propose a new two-step metabolic hit model for TED in the progression of DNP.
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