Example sentences for: mao-b

How can you use “mao-b” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Analysis of biophores #1, #2 (#4, #5) showed that both of them occur in substituted 5-[4-(benzyloxy) phenyl]-1,3,4-oxadiazol-2-(3H)-ones and their analogs (Figure 1), many of which are known to be strong MAO-B inhibitors [ 9 ] . Biophore #2 represents a flexible -CH 2 O- bridge between aryl moieties and was found to enhance the activity and selectivity of the inhibitors as shown in the original work [ 9 ] . Biophores #1 and #2 include aromatic moieties, whose main function is presumably to bind to the hydrophobic site of MAO.

  • Under these conditions all compounds that inhibit the MAO-B enzyme were treated as "active" and the others as "inactive".

  • MAO inhibitors which ratio was within 0.1-10 range were considered as unselective MAO-B inhibitors and were treated as "marginally active" molecules.

  • Two types of precursors of active MAO-B inhibitors were identified.

  • These compounds are known to be time-dependent inhibitors of MAO-B [ 22 ] .


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