Words similar to mammary
Example sentences for: mammary
How can you use “mammary” in a sentence? Here are some example sentences to help you improve your vocabulary:
A recent study of βERKO mice has shown that ERβ is not required for the normal prepubertal development of the mammary gland but for organization and adhesion of epithelial cells during pregnancy and hence for differentiated tissue morphology [ 23 ] . These observations indicate a possibility of complementary (sequential) roles of ERα and ERβ, since ERα appears to be required for the basic development of estrogen sensitive tissues and ERβ seems to be required for their functional maturation.
SL-1 induction in p2S cells, an untransformed mouse mammary epithelial cell line, triggered the disappearance of E-cadherin and beta-catenin from cell-cell junctions and reduced the expression of beta-catenin [ 35 ] . Wnt-5a and SL-1 may play similar roles in inhibiting cadherin-mediated cell-adhesion, as Wnt-5a decreases Ca 2+-dependent cell adhesion similar to a dominant negative cadherin [ 11 ] . The regulation of SL-1 by Wnt-5a may be important in developmental processes such as gastrulation where Wnt-5a affects the morphogenetic movement of tissues [ 45 ] .
A summary of the differences in the molecular status and cell cycle profile between TM10 and TM2H cell lines before SAHA treatment are summarized in Table 1. These differences in p21 protein and BrdU index were predicted based on p53 status of these two cell lines and are in parallel with other reports on mammary tumors, where the absence of p53 results primarily in greater proliferation response in the affected cell [ 42].
Accelerated appearance of mammary adenocarcinomas in the presence of a Pten mutation suggests a synergy between Pten inactivation and the Wnt-1 transgene.
These observations differ from a recent report that one of the other two Pten +/- lines develops fibroadenomas and adenocarcinomas in the mammary tissue after 7 months of age [ 26].