Words similar to malignant
Example sentences for: malignant
How can you use “malignant” in a sentence? Here are some example sentences to help you improve your vocabulary:
The mass media's "moral pollution" is "actual and malignant."
There have been some spectacular successes, in particular with immune therapy to malignant melanoma, a tumor type that seems naturally to be more immunogenic than others.
Comparative differences between benign and malignant nodal groups were highest for T2* and pixel variance measurements (see Table 3).
A summary of the operations performed on those 32 patients admittedpostoperatively to the SCU is shown in Table 2.Twenty-six patients were operated upon electively and six patients emergently.Sixteen patients underwent resection of malignant disease with curative intent,six underwent treatment for benign disease, six had palliative operations, andfour received treatment for complications of a surgical procedure performedduring a previous hospital admission.
First, PTEN's protein phosphatase activity is able to down-regulate focal adhesion kinase (FAK) phosphorylation, which leads to the inactivation of the Ras/MAP kinase pathway [ 19 20 21 ] . Second, its lipid phosphatase activity targets the second messenger phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P 3 ] and thereby blocks activation of the protein kinase B (PKB/Akt) pathway [ 11 18 22 23 24 ] . Whereas both of the above pathways are intimately involved in the control of cell growth and survival, PTEN-regulated FAK activity further appears to impinge on cell adhesion, cell migration, and cell invasion [ 20 21 ] . It therefore emerges that the loss of PTEN activity may confer increased survival ability, proliferative potential, and invasive capacity on cells, and thereby may promote progression towards a more malignant phenotype.
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