Example sentences for: malignancies

How can you use “malignancies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although less frequent, 1p gains are also common to many tobacco-associated malignancies [ 11 13 14 15 16 ] . Work by Racz and colleagues suggest that PAX7 and ENO1 may be candidate oncogenes in this region [ 21 ] . PAX7 is part of a family of transcription factors known to be carcinogenic.

  • Dong and co-workers also previously showed promoter methylation in 51% of CC [ 13 ] . DAPK is a positive mediator of the programmed cell death induced by gamma-interferon [ 21 ] . Loss of DAPK expression has been shown to occur in a number of human malignancies, primarily by promoter hypermethylation [ 11 ] . It has also been shown that loss of DAPK gene expression was associated with aggressive and metastatic phenotype in many tumor types [ 22 ] . In the present study, in addition to showing high frequency of promoter methylation of DAPK gene, we found a complete lack of expression in two of the methylated cell lines and four of 6 unmethylated cell lines.

  • The underlying co-morbid conditions we considered included chronic lung disease, chronic renal disease, diabetes, malignancies, HIV infections, chronic heart disease, and chronic renal disease.

  • The delirium rate is 10-40% in cancer patients [ 23], but increases to 85% in patients with advanced malignancies [ 15].

  • Current immunosuppressive regimens are capable of preventing islet failure for months to years, but the agents used in these treatments are expensive and may increase the risk for specific malignancies and opportunistic infections.


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