Example sentences for: malignancies

How can you use “malignancies” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • ICD-O (International Classification of Diseases - Oncology) lists virtually no precancerous lesions [ 9 ] . The ICD-O is used by cancer registrars to annotate, in a uniform way, cases of treated malignancies.

  • Furthermore, these results imply that aberrant BP1 expression might also be involved in other malignancies.

  • Criteria for exclusion from the study were as follows: already known pre-existing adrenal disease or adrenalectomy, known malignancies, tuberculosis that might have involved the adrenal gland, and administration of steroids within the 3 months before the admission.

  • 9 y) with histologically proven malignancies from different primaries (Table 1), including prostate ( n = 18), breast ( n = 7), penile ( n = 4), bladder ( n = 2), testes ( n = 2), and colon ( n = 1).

  • In response to DNA damage induced by ionizing radiation or chemical agents such as cisplatin, ATM kinase is activated and phosphorylates a number of downstream regulatory proteins important for cell cycle arrest, growth control, apoptosis and DNA repair [ 25 26 27 28 ] . AT patients are known to be predisposed to a variety of cancers, and the fibroblasts of AT patients are hypersensitive to ionizing radiation [ 29 ] . Although many reports showed the association of ATM mutation with risk of a number of different human malignancies, including prostate cancer, breast cancer, ovarian cancer, B-cell chronic lymphocytic leukemia and mantle cell lymphoma, the underlying molecular mechanism by which ATM gene causes these changes are not well understood [ 30 31 32 33 34 35 ] . There is so far no study showing the association of ATM gene with any solid tumor.


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