Example sentences for: malformations

How can you use “malformations” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Wnt activation in the adult hippocampus, cortex and cerebellum did not result in tumors or other CNS malformations.

  • Finally, mutation of a factor required to load cohesin—the protein complex responsible for chromosome cohesion—onto chromosomes appears to cause Cornelia de Lange syndrome, a clinically heterogeneous developmental disorder that may include facial dysmorphia, upper-extremity malformations, hirsutism, cardiac defects, growth and cognitive retardation, and gastrointestinal disorders [3,4,5].

  • In addition, changes in neuronal cell size distribution in the medial geniculate nuclei associated with the presence of neocortical malformations, have been demonstrated in both human dyslexic brains [ 13 ] and rat brains [ 14 15 16 ] .

  • Neural tube defects (NTDs) are major malformations of the central nervous system (CNS) due to a defect in the covering of the CNS.

  • For example, the presence of neocortical malformations in certain strains of inbred mice are correlated with better performance on tasks of spatial reference memory [ 17 18 ] . On the other hand, induced microgyric animals show a variety of behavioral deficits that suggest disturbances to multiple brain systems [ 15 19 20 21 22 ] . Rapid auditory processing deficits have been found in males with induced microgyria using both an operant condition paradigm and a reflex modification paradigm [ 15 19 20 21 ] . In both paradigms, auditory processing deficits were found only on rapidly changing stimuli, and not when these same stimuli were delivered at slower rates.


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