Words similar to malformations
Example sentences for: malformations
How can you use “malformations” in a sentence? Here are some example sentences to help you improve your vocabulary:
In addition, changes in neuronal cell size distribution in the medial geniculate nuclei associated with the presence of neocortical malformations, have been demonstrated in both human dyslexic brains [ 13 ] and rat brains [ 14 15 16 ] .
It has been shown that these malformations, resembling human microgyria, are associated with widespread disturbances in neuronal organization [ 4 5 ] . For example, brain slices containing microgyric cortex show increased epileptogenic activity [ 6 7 8 9 ] . Microgyric anomalies are also associated with connectional alterations [ 10 11 12 ] , affecting both thalamic and cortico-cortical connectivity.
Wnt activation in the adult hippocampus, cortex and cerebellum did not result in tumors or other CNS malformations.
Several genes expressed specifically in the normal male foreskin fibroblasts have been previously implicated in male genital development, including HOXA13 , the T-box genes, BMP4 and DWnt2 . Mutations in HOXA13 can cause distal limb and urogenital-tract malformations such as male hypospadias in hand-foot-genital syndrome [ 21 ] . T-box genes ( TBX ) are essential early regulators of limb development and also appear to be involved in male genital development [ 22 23 ] . Mutations in TBX3 cause the ulnar-mammary syndrome characterized by limb, apocrine, and genital developmental abnormalities [ 23 ] . Expression of T-box genes 2, 3, and 5 was significantly higher in normal male foreskin fibroblasts than in AIS genital fibroblasts.
Neural tube defects (NTDs) are major malformations of the central nervous system (CNS) due to a defect in the covering of the CNS.
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