Example sentences for: malformations

How can you use “malformations” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Neural tube defects (NTDs) are major malformations of the central nervous system (CNS) due to a defect in the covering of the CNS.

  • They are among the most prevalent of congenital malformations.

  • In addition, changes in neuronal cell size distribution in the medial geniculate nuclei associated with the presence of neocortical malformations, have been demonstrated in both human dyslexic brains [ 13 ] and rat brains [ 14 15 16 ] .

  • Wnt activation in the adult hippocampus, cortex and cerebellum did not result in tumors or other CNS malformations.

  • Several genes expressed specifically in the normal male foreskin fibroblasts have been previously implicated in male genital development, including HOXA13 , the T-box genes, BMP4 and DWnt2 . Mutations in HOXA13 can cause distal limb and urogenital-tract malformations such as male hypospadias in hand-foot-genital syndrome [ 21 ] . T-box genes ( TBX ) are essential early regulators of limb development and also appear to be involved in male genital development [ 22 23 ] . Mutations in TBX3 cause the ulnar-mammary syndrome characterized by limb, apocrine, and genital developmental abnormalities [ 23 ] . Expression of T-box genes 2, 3, and 5 was significantly higher in normal male foreskin fibroblasts than in AIS genital fibroblasts.


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