Words similar to malformation
Example sentences for: malformation
How can you use “malformation” in a sentence? Here are some example sentences to help you improve your vocabulary:
Preliminary reports have linked ligands active at the GABA receptor with SB or other NTDs, including benzodiazepines, alcohol, and zinc [ 7 8 9 10 11 ] . Preliminary work from this laboratory has shown the GABAa receptor agonist muscimol and the GABAb agonist baclofen produce both SB and the Arnold-Chiari malformation, commonly associated with SB [ 12 13 14 ] . VA appears to produce most of its anticonvulsant effects by increasing levels of GABA in the CNS, presumably by inhibiting the enzyme GABA-transaminase (GABA-T).
There was no obvious lytic change or periostosis; however, there were flow voids consistent with a vascular malformation.
The finding that A. pisum embryos maintained at 16°C showed considerable malformation may be a consequence of surpassing the normal thermal limits of developmental regulation.
Interpreting these data is, however, problematic, as a high proportion of 16°C embryos showed moderate to severe developmental malformation, making measurement of body and leg length difficult.
It is interesting to note, however, that in newborn mice a brief local application of 2 mM domoic acid to the exposed cortical surface led to a massive degeneration of AMPA/KA GluR receptor positive Cajal-Retzius neurons [ 44 ] , severe impairment of cortical neuronal migration in vivo and malformation of the domoic acid-treated neocortex [ 44 ] . Thus, because 1 mM domoic acid was clearly toxic to cerebellar granule neurons both in vitro (our current study) and in vivo [ 44 ] , we selected 1 mM domoic acid for the experiments with rat neonatal microglia reported herein.
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