Words similar to malabsorption

Example sentences for: malabsorption

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Untreated children and adults with cystic fibrosis excrete amounts of fecal bile acids similar to patients with ileal resections [ 20 21 ] . Based on kinetic studies, this increased fecal loss appears to be secondary to an interrupted enterohepatic circulation of bile acids [ 20 21 ] . Bile acid malabsorption in cystic fibrosis appears to be due in part to diminished secretion of pancreatic enzymes and the presence of un-hydrolyzed triglycerides.
Supplementation with pancreatic enzymes and a low-fat diet can markedly reduce the fecal excretion of bile acids [ 9 10 20 23 ] . Other evidence, however, suggests that a diminished capacity of the ileal mucosa for bile acid uptake plays a significant role in bile acid malabsorption associated with cystic fibrosis that is independent of triglyceride concentrations.
Bile acid malabsorption in CF has been attributed to an inhibitory effect of un-hydrolyzed, intraluminal triglycerides on the intestinal absorption of bile acids.
They found a decrease in total (apical + basolateral) bile acid uptake compared to normal controls [ 12 ] and hypothesized that bile acid malabsorption in cystic fibrosis was due to a primary mucosal defect although they had not specifically studied apical, Na +-dependent absorption.
In contrast, cftr (-/-) mice may experience bile acid malabsorption even though their ileal mucosal cells express four-fold more IBAT transporters than normal cells.