Example sentences for: malabsorption

How can you use “malabsorption” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The results indicate that bile acid malabsorption in CF is not caused by a defect in sodium-dependent bile acid transport at the brush border membrane suggesting another mechanism is operative.

  • However, in several studies the correlation between fecal fat excretion and fecal bile acid loss could not be demonstrated, suggesting that additional factors are responsible for bile acid malabsorption in cystic fibrosis [ 9 10 ] . In vitro studies using brush border membrane vesicles or bathed tissue samples from patients with cystic fibrosis have shown that total ileal bile acid uptake is diminished [ 11 12 ] .

  • Although generally thought to have a later presentation [ 1 ] than other primary intestinal malabsorption syndromes, recent reports of infants with SI deficiency indicate the existence of an early onset form (presentation of diarrhea at 2-16 weeks) that is complicated by severe malnutrition [ 2 ] . Starnes and Walsh [ 3 ] observed renal calculi in two adults with sucrase deficiency, but neither patient had evidence of hypercalcemia.

  • Supplementation with pancreatic enzymes and a low-fat diet can markedly reduce the fecal excretion of bile acids [ 9 10 20 23 ] . Other evidence, however, suggests that a diminished capacity of the ileal mucosa for bile acid uptake plays a significant role in bile acid malabsorption associated with cystic fibrosis that is independent of triglyceride concentrations.

  • They found a decrease in total (apical + basolateral) bile acid uptake compared to normal controls [ 12 ] and hypothesized that bile acid malabsorption in cystic fibrosis was due to a primary mucosal defect although they had not specifically studied apical, Na +-dependent absorption.


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