Example sentences for: lyn

How can you use “lyn” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because Fyn is expressed in T cells and Hck and Lyn are not, we pursued the connection between Rlk and the T cell-specific isoform p59 FynT.

  • Some of the earliest changes that occur following BCR engagement are the activation of several non-receptor protein tyrosine kinases (PTKs), including p55 blk (Blk), p59 fyn (Fyn) and p53/56 lyn (Lyn) of the Src family [ 31 ] , Btk of the Itk/Tec family [ 32 33 ] and p72 Syk (Syk) of the Syk/ZAP-70 family [ 34 ] . The importance of Syk in BCR signaling and lymphocyte development has been clearly demonstrated using gene inactivation approaches.

  • Thus, in a recent report ionotropic AMPA glutamate receptors were shown to " ...function not only as ion channels but also as cell-surface transducers by means of their interaction with the Src-family non-receptor protein kinase Lyn.

  • Moreover, the relatively weak phosphorylation of cellular proteins induced by Btk:ER does not suggest that Lyn and/or Syk are becoming activated (Fig 1C).

  • Additionally, the sustained PLCγ2 phosphorylation induced by Btk:ER is in agreement with the idea that Btk does not activate negative regulatory pathways that turn off the signal; rather it is Lyn that is thought to be largely responsible for this aspect of BCR signaling [ 15].


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