Words similar to lyn

Example sentences for: lyn

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Some of the earliest changes that occur following BCR engagement are the activation of several non-receptor protein tyrosine kinases (PTKs), including p55 blk (Blk), p59 fyn (Fyn) and p53/56 lyn (Lyn) of the Src family [ 31 ] , Btk of the Itk/Tec family [ 32 33 ] and p72 Syk (Syk) of the Syk/ZAP-70 family [ 34 ] . The importance of Syk in BCR signaling and lymphocyte development has been clearly demonstrated using gene inactivation approaches.
GST fusions encoding the Rlk amino-terminal and SH3 domains or the amino-terminus alone (containing the cysteine string and proline-rich region) bound biotinylated GST fusions of the SH3 domains of Fyn, Hck, and Lyn, but not those of Src or Lck, despite the ability of these constructs to bind other proline rich sequences (Fig.
Because Fyn is expressed in T cells and Hck and Lyn are not, we pursued the connection between Rlk and the T cell-specific isoform p59 FynT.
These proteins are unlikely to include Lyn or Syk, the two PTKs that are primarily responsible for the BCR-induced tyrosine phosphorylation pattern seen in DT40 whole cell lysates [ 14], since we were unable to detect phosphorylation of Lyn and Syk following specific immunoprecipitations (data not shown).
During the last Congress, Gingrich rehabilitated convicted felon Michael Deaver as a Republican adviser in good standing, while the Dole campaign brought such notorious sleaze-meisters as Lyn Nofziger, Paul Manafort, Charlie Black, and John Sears back into the fold.